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A kind of traditional Chinese medicine preparation for treating stomach disease and its preparation method and detection method

A technology for traditional Chinese medicine preparations and detection methods, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, and measuring devices, etc., can solve the problems of large dosage, strong nephrotoxicity, and low dissolution rate of finished products.

Active Publication Date: 2011-12-14
贵州三仁堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Aokiba contains aristolochic acid in this prescription, which has strong nephrotoxicity, and the State Food and Drug Administration has canceled the medicinal standard of Aokiba; and the drug is a raw powder preparation, and the process is relatively simple. The relationship between the particle size of the medicinal flavor and the efficacy of the medicine is simply crushed with a uniform particle size for each medicinal flavor in the opponent, resulting in low dissolution and poor bioavailability of the finished product, failing to fully exert the drug effect and affecting the efficacy of the drug. larger

Method used

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  • A kind of traditional Chinese medicine preparation for treating stomach disease and its preparation method and detection method
  • A kind of traditional Chinese medicine preparation for treating stomach disease and its preparation method and detection method
  • A kind of traditional Chinese medicine preparation for treating stomach disease and its preparation method and detection method

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Experimental program
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Effect test

Embodiment 1

[0267] Embodiment 1: the preparation of the micropowder capsule for the treatment of gastropathy:

[0268] Weigh 42g of Xuedan, 32g of Golden Buckwheat, 32g of Daxueteng, 21g of Purple Pearl, 32g of Burlap Bag, 32g of Corydalis Corydalis, 32g of Agrimony, 63g of Baiji, 42g of Phoenix Clothes, 32g of Tumuxiang and 40g of Walnut Kernel, and grind them into Micropowder of the above fineness: Snow Gallbladder 20-40μm, Golden Buckwheat 60-80μm, Sacred Rhizoma 60-80μm, Purple Pearl 100-125μm, Burlap Bag 20-40μm, Corydalis 40-60μm, Agrimony 100-125μm, White and 60-80 μm, phoenix clothes 150-180 μm, inulin 125-150 μm, walnut kernel 150-180 μm; mix the aforementioned micropowders and put them into capsules to obtain micropowder capsules. The preparation is taken orally, 3 capsules each time, 3 times a day.

Embodiment 2

[0269] Embodiment 2: the preparation of the granule for treating stomach disease:

[0270] Weigh 40g Xuedan, 30g Golden Buckwheat, 30g Daxueteng, 20g Zizhu, 30g burlap bag, 30g Corydalis, 30g Agrimony, 60g Baiji, 40g Phoenix Clothes, 30g Tumuxiang and 38g walnut kernels, and crush them into Micropowder of the above fineness: Snow Gallbladder 20-40μm, Golden Buckwheat 60-80μm, Sacred Rhizoma 60-80μm, Purple Pearl 100-125μm, Burlap Bag 20-40μm, Corydalis 40-60μm, Agrimony 100-125μm, White and 60-80 μm, phoenix clothing 150-180 μm, inulin 125-150 μm, walnut kernel 150-180 μm; mix the above-mentioned micropowders with appropriate amount of auxiliary materials to make sugar-containing granules or sugar-free granules, dry, granulate, and pack. Get granules. The preparation is taken orally, and the granules containing 1.2 g of medicinal powder are taken each time, 3 times a day.

Embodiment 3

[0271] Embodiment 3: the preparation of the oral preparation of traditional Chinese medicine for the treatment of gastropathy:

[0272] Weigh 44g of snow gall, 34g of golden buckwheat, 34g of Daxueteng, 22g of purple pearl, 34g of sackcloth, 34g of Corydalis 34g, 34g of Agrimony, 66g of Baiji, 44g of Phoenix clothes, 34g of Tumuxiang and 42g of walnut kernels, and crush them into 20g respectively. ~180μm micropowder, mix well, and make various oral dosage forms according to conventional methods.

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating gastropathy and a preparation method and a detection method thereof. The preparation is prepared by the following herbs by weight: 40-44 parts of radix hemsleyae, 30-34 parts of wild buckwheat Rhizome, 30-34 parts of sargentgloryvine stem, 20-22 parts of beautyberry, 30-34 parts of gunny, 30-34 parts of rhizoma corydalis, 30-34 parts of herba agrimoniae, 60-66 parts of bletilla rhizome, 40-44 parts of membrana follicularis ovi, 30-34 parts of elecampane, and 38-42 parts of walnut kernels. By using elecampane instead of aristolochia debilis in Shuangjinweiyang capsules, the traditional Chinese medicine preparation prepared by the invention has the same efficacy of smoothing liver and rectifying qi, strengthening stomach and relieving pain, convergence and haemostasis, and the drug efficacy is more significant. In addition, the toxic and side effect of aristolochia debilis is removed in the formula, and the safety of the drug is greatly improved; the medicinal materials are pulverized into fine powder during preparation, which increases the dissolubility and bioavailability of the finished product, and brings the efficacy into full play; the newly-established detection method has high precision, good stability, and accurate measurement results, can effectively control the product quality, and thus can ensure the clinical curative effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating stomach diseases, a preparation method and a detection method thereof, and belongs to the technical field of traditional Chinese medicine pharmacy. Background technique [0002] Stomach disease is actually a general term for many diseases; they have similar symptoms, such as upper abdominal discomfort or pain, nausea, vomiting, diarrhea, loss of appetite, and the symptoms of gastric and duodenal ulcers are burning pain in the upper abdomen, severe cases May have tar stool, black stool or bloody stool and so on. Clinically common gastric diseases include acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, gastric duodenal ulcer, gastric polyps, gastric stones, benign and malignant gastric tumors, gastric mucosal prolapse, acute Gastric dilatation, pyloric obstruction, etc. There are a variety of Western medicines or traditional Chinese medicines or other tr...

Claims

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Application Information

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IPC IPC(8): A61K36/898G01N30/90G01N30/02A61P1/04A61P1/00A61K35/48A61K35/57
Inventor 孙玉存黄良勤周方勇
Owner 贵州三仁堂药业有限公司
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