Methods and systems for determining phenotypes using exosomes

A phenotypic, exosome-based technology, applied in 25 fields, can solve the problems of expensive, lack of specificity, lack of sensitivity of readout, etc.
CN102301002AInactive Publication Date: 2011-12-28CARIS LIFE SCI LUXEMBOURG HLDG
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CARIS LIFE SCI LUXEMBOURG HLDG
Publication Date
2011-12-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

Exosomes can be used for detecting biomarkers for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, for example, the stage or progression of a disease. Cell-of-origin exosomes can be used in profiling of physiological states or determining phenotypes. Biomarkers or markers from cell-of-origin specific exosomes can be used to determine treatment regimens for diseases, conditions, disease stages, and stages of a condition, and can also be used to determine treatment efficacy. Markers from cell-of-origin specific exosomes can also be used to identify conditions of diseases of unknown origin.
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Description

[0001] cross reference

[0002] This application claims Serial No. 61 / 114,045 filed November 12, 2008, Serial No. 61 / 114,058 filed November 12, 2008, Serial No. 61 / 114,065 filed November 13, 2008, February 2009 No. 61 / 151,183 filed on October 9, No. 61 / 278,049 filed on October 2, 2009, No. 61 / 250,454 filed on October 9, 2009, and No. 61 filed on October 19, 2009 / 253,027, each of which is hereby incorporated by reference in its entirety. Additionally, this application is a related application of U.S. Application No. 12 / 609,847, filed October 30, 2009, which claims U.S. Provisional Application No. 61 / 109,742, filed October 30, 2008, No. 61 / 112,571 filed on November 7, No. 61 / 114,045 filed on November 12, 2008, No. 61 / 114,058 filed on November 12, 2008, No. 61 filed on November 13, 2008 / 114,065, No. 61 / 151,183 filed February 9, 2009, No. 61 / 278,049 filed October 2, 2009, No. 61 / 250,454 filed October 9, 2009, and October 19, 2009 Priority to Ser. No. 61 / 253,027 filed on , each ...

Claims

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