Hypnotic Chinese medicinal preparation for external use

The technology of a traditional Chinese medicine preparation and sleeping patch, which is applied in the field of sleeping traditional Chinese medicine preparations, can solve the problems of insufficient lasting effect, trauma and the like, and achieve the effect of convenient side effects.

Active Publication Date: 2012-01-11
YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE
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  • Summary
  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although traditional Chinese medicine and acupuncture are effective in treating insomnia, the existing Chinese medicines for treating insomnia are a...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The ingredients and production conditions of the sleeping Chinese medicine preparation for external use:

[0034] Table 1 Ingredients list of sleeping medicine preparations

[0035]

[0036] The preparation method of the hypnotic traditional Chinese medicine preparation for external use: ginseng, astragalus, angelica, schisandra, calamus and polygala are respectively dried and pulverized according to the weight shown in the ingredient list, passed through a 100-mesh sieve and mixed. The mixture is mixed with maltose, alcoholic aqueous solution, laurocapram (formulated into a 3wt% aqueous solution) and water into the weight shown in the ingredient list, mixed evenly and stirred, and the obtained paste concoction is the sleeping Chinese medicine preparation for external use .

Embodiment 2

[0038] Making sleeping stickers:

[0039] The sleeping patch comprises: a sleeping drug layer, a backing layer and an inner lining layer. One side of the backing layer is a viscose surface, and the hypnotic drug layer is located in the middle of the viscose side of the backing layer, and the hypnotic drug layer is made from 2 g of the external hypnotic Chinese medicine preparation of formula IV in Example 1 , the sleeping drug layer is enclosed by the backing layer and the inner lining layer, and the area of ​​the sleeping drug layer is 35% of the area of ​​the backing layer.

Embodiment 3

[0041] The therapeutic effect of the externally used hypnotic Chinese medicine preparation on insomnia patients:

[0042] A. Test substance: sleeping patch prepared in Example 2.

[0043] B. Negative control drug: flour, maltose and 15v% alcohol are mixed in a weight ratio of 2: 4: 1, add laurocaprazine aqueous solution (3wt%) accounting for 2wt% of flour, mix and stir, and the resulting paste concoction The control patch was prepared according to the method described in Example 2.

[0044] C. Experimental subjects: select 100 cases of insomnia patients who meet the diagnostic criteria for insomnia in the International Classification of Sleep Disorders (ICSD) formulated by the American Sleep Disorders Association (ASDA), and divide the patients into 2 groups according to the random number table (the sleep patch group) and blank control group), 50 cases in each group.

[0045] Diagnostic criteria

[0046] a) Decreased physical function in a state of sleep disturbance;

[00...

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PUM

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Abstract

Relating to the Chinese medicinal preparation field, the invention provides a hypnotic Chinese medicinal preparation for external use. The preparation consists of main effective components and accessories, wherein the main effective components include ginseng, astragalus, Angelica sinensis, Schisandra chinensis, Acorus tatarinowii Schott and polygala. As a Chinese medicinal product, the hypnotic Chinese medicinal preparation provided in the invention, compared with western medicines, has the characteristics of safety, effectiveness and no dependence. And the hypnotic Chinese medicinal preparation is a Chinese medicinal product with external administration. Delivered through skin, the Chinese medicinal preparation of the invention has the advantages of high efficiency, low toxicity, safety, convenience and rapidness, etc.

Description

technical field [0001] The invention provides an external hypnotic traditional Chinese medicine preparation, its preparation method and its application in the preparation of medicine or preparation for diagnosing or treating insomnia. Background technique [0002] Insomnia is a sleep disorder and a common clinical manifestation of various physical, mental and behavioral diseases. Long-term insomnia can lead to negative results such as reduced thinking agility, memory loss and slow movement, which seriously affects people's physical and mental health, quality of life and work efficiency. According to the results of the latest global sleep survey in China released by the Psychiatry Branch of the Chinese Medical Association, the number of people with insomnia in China is as high as 42.5%, and it is on the rise. According to the 2006 survey on the insomnia status of the general population in six cities in China: the prevalence of insomnia among adults is 57%, and the insomnia c...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61K9/70A61P25/20
Inventor 杨文佳陈云飞于心同邴兴红谢晨李连波陈潇毅
Owner YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE
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