Eucommia active monomer compound as well as preparation method, pharmaceutical composition and application thereof

A technology of active monomers and compounds, applied in the field of active monomers of traditional Chinese medicine and their preparation, can solve the problems of unclear active ingredients and action mechanism, and the application of Eucommia active monomer compounds has not yet been seen, and achieves stable and easy separation process, Abundant sources and positive effects
CN102320928BInactive Publication Date: 2014-05-07HENAN UNIV OF SCI & TECH
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
HENAN UNIV OF SCI & TECH
Publication Date
2014-05-07
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a eucommia active monomer compound, the structural formula of which is shown in the specification. The invention also discloses a preparation method of the compound, a pharmaceutical composition containing the compound and pharmaceutical application of the compound. The active monomer compound is extracted from eucommia and can be extracted from eucommia bark, eucommia leaves, eucommia male flowers, eucommia seeds or whole eucommia plants. The extracted active monomer compound is 4-hydroxy-3-(2-hydroethyl)-1-cyclopentene-1,2-dimethanol, and experiments prove that the compound has obvious sedation, hypnogenesis, anti-convulsion and other effects as well as no side effect and dependence, and can be taken for a long time. The active monomer compound extracted from eucommia and the effects of the compound in the aspects of sedation, hypnogenesis, anti-convulsion and the like are provided in the invention, thereby providing a novel natural active substance for researching and developing novel health-care food and novel sedative-hypnotic drugs.
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Description

technical field

[0001] The invention relates to the technical field of active monomers of traditional Chinese medicine and the preparation thereof, in particular to an active monomer compound of eucommia ulmoides, a preparation method, a pharmaceutical composition and its application. Background technique

[0002] Insomnia is a clinical frequently-occurring disease with complex etiology and easy recurrence. Insomnia seriously affects people's life, work and physical and mental health. The incidence of serious accidents and trauma caused by long-term insomnia is significantly higher than that of normal sleepers. Insomnia, if left untreated, can lead to disturbances in metabolism and systemic function, causing significant changes in mood, behavior, and psychomotor function.

[0003] Drug therapy is one of the most important means for the treatment of insomnia. The effect of sedative hypnotics can make the patient's tension, irritability, insomnia and other mental overexcite...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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