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Sterilization composition containing zhongshengmycin

A technology of bacteriocin and composition, which is applied in the field of bactericidal composition containing zhongshengmycin, can solve problems such as difficulty in obtaining good control effects, unscientific farming methods, and irrational drug use, so as to reduce drug costs and reduce The effect of drug dosage and efficacy improvement

Inactive Publication Date: 2013-07-17
广西德丰富化工有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In recent years, due to unscientific farming methods and irrational use of drugs, fungal and bacterial diseases in the field have become more and more serious, such as cucumber horn spot, root rot, fusarium wilt, bacterial wilt, etc. Difficult to achieve better control effect
[0003] Zhongshengmycin is a biological N-glycoside antibiotic with a broad antibacterial spectrum and is effective against a variety of bacteria and fungi, especially for Gram-negative and positive bacteria; its mechanism of action is by inhibiting The peptide bond formation of pathogenic bacterial protein will eventually lead to the death of bacteria; it has a strong inhibitory effect on the germination of fungal pathogenic spores, causing protoplasm condensation in mycelial cells, changing the shape of mycelium, and preventing and controlling fungal diseases; its target : Wide antibacterial spectrum, can resist Gram-positive and negative bacteria, mycobacteria, yeast and filamentous fungi, especially for crop pathogens such as cabbage soft rot, cucumber horn spot, rice bacterial blight, apple Ringworm bacteria, etc. have obvious antibacterial activity, but the cost of Zhongshengmycin is high when used alone, and the risk of resistance is high when it is used continuously for a long time

Method used

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  • Sterilization composition containing zhongshengmycin
  • Sterilization composition containing zhongshengmycin
  • Sterilization composition containing zhongshengmycin

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0033] Indoor Toxicity Determination of Zhongshengmycin and Fludioxonil to R. solanacearum of Watermelon

[0034] Test object: watermelon blight

[0035] Test method: The test adopts the mycelium growth rate method. See Table 1 for the test agent. Take 5ml of the drug solution and add it to an Erlenmeyer flask equipped with 45ml of hot medium (PDA medium, 45-50°C). After shaking well, quickly pour it into a 90mm diameter glass petri dish. Pour 12ml of medium with medicine into it, 4 replicates for each treatment, place it horizontally, and form a flat plate after cooling, and mix an equal amount of sterile water with the medium as a control. Use a puncher with a diameter of 5mm to cut the fungus cake from the edge of the test bacteria that has been cultured for 2 days, and connect the side with mycelium to the poisonous medium with a pick needle. All operations are performed aseptically on the ultra-clean workbench. After treatment, they were placed in a constant temperature...

example 2

[0047] Toxicity determination of Zhongshengmycin and fludioxonil compound against tomato damping-off pathogen

[0048] Test object: Tomato damping-off fungus

[0049] Test method and statistical analysis method are the same as biological assay example 1

[0050] It can be seen from Table 2 that when the proportion of Zhongshengmycin and fludioxonil is between 1~10:50~1, the co-toxicity coefficient to watermelon blight is above 120, especially when the proportion is 1~5 : The co-toxicity coefficient between 30 and 1 is above 200, and the synergistic effect is remarkable.

[0051] Table 2 Indoor toxicity test results of the combination of shengmycin and fludioxonil against tomato pathogens

[0052] potion

[0053] The present invention will be further described below in conjunction with embodiment. But it does not limit the scope of the present invention. Unless otherwise specified, the contents in the examples are all in mass percentages, and the used pharmaceutic...

Embodiment 1

[0054] Embodiment 1 prepares 2% Zhongshengmycin·fludioxonil suspension concentrate

[0055] Weigh: Zhongshengmycin 10g, fludioxonil 10g, wetting and penetrating agent T 10g, NNO 10g, carboxymethylcellulose 15g, propylene glycol 30g, water 915g, 1Kg in total.

[0056] The above-mentioned components are fully mixed and put into a sand mill for fine processing to obtain 1Kg of 2% Zhongshengmycin · Fludioxonil suspension concentrate.

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PUM

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Abstract

The invention discloses a sterilization composition containing zhongshengmycin, which uses zhongshengmycin and fludioxonil as effective ingredients, and the mass ratio of the zhongshengmycin to the fludioxonil is (1 to 10) / (50 to 1). The sterilization composition has the preparations of wettable powder, suspension agents and water dispersing agents. The sterilization composition has the followingadvantages that: 1, the sterilization spectrum is enlarged, the synergia effect is obvious, and the prevention and treatment effects are improved; 2, the zhongshengmycin and the fludioxonil are two medicaments with different action mechanisms, and the resistance risk is reduced when the zhongshengmycin and the fludioxonil are mixed and matched; and 3, the zhongshengmycin and the fludioxonil are compounded, the medicine effect is improved, the medication quantity is reduced, the medication cost is reduced, and the residue and the relative environment pollution are reduced.

Description

technical field [0001] The invention belongs to the field of pesticides, in particular to a bactericidal composition containing Zhongshengmycin. Background technique [0002] In recent years, due to unscientific farming methods and irrational use of drugs, fungal and bacterial diseases in the field have become more and more serious, such as cucumber horn spot, root rot, fusarium wilt, bacterial wilt, etc. It is difficult to obtain better control effect. [0003] Zhongshengmycin is a biological N-glycoside antibiotic with a broad antibacterial spectrum and is effective against a variety of bacteria and fungi, especially for Gram-negative and positive bacteria; its mechanism of action is by inhibiting The peptide bond formation of pathogenic bacterial protein will eventually lead to the death of bacteria; it has a strong inhibitory effect on the germination of fungal pathogenic spores, causing protoplasm condensation in mycelial cells, changing the shape of mycelium, and prev...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/36A01N43/16A01P3/00A01P1/00
Inventor 迟海军韦荣相史万琪谭贤勇
Owner 广西德丰富化工有限责任公司
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