Preparation and quality detection methods of high-purity honeysuckle flower-baikal skullcap root soluble powder

Abstract

The invention discloses preparation and quality detection methods of high-purity honeysuckle flower-baikal skullcap root soluble powder. The preparation method comprises the following steps of: 1, preparing an appropriate amount of baikal skullcap root, adding water for decocting for 2-4 times, combining decoctions, filtering, and concentrating the filtrate till the relative density is 1.10-1.35; 2, regulating the pH value to 1.0-2.0 with hydrochloric acid, preserving heat at the temperature 60-80 DEG C, standing, and filtering; 3, adding water into a precipitate, stirring uniformly, and regulating the pH value to 6.5-7.5 with 30-40 percent sodium hydroxide; 4, adding an equal amount of ethanol, stirring for dissolving, filtering, regulating the pH value of the filtrate to 1.0-2.0 with hydrochloric acid, preserving heat at the temperature 60-80 DEG C, standing, and filtering; 5, washing the precipitate with an appropriate amount of water and ethanol of different concentrations in sequence till the pH value is 6.5-7.5; 6, vaporizing the ethanol and drying under reduced pressure to obtain a baikal skullcap root extract; 7, preparing an appropriate amount of honeysuckle flower, adding water for decocting for 1-3 times, combining decoctions, filtering, and concentrating the filtrate under reduced pressure at the temperature 50-70 DEG C till the relative density is 1.10-1.25 to obtain clear paste; 8, adding ethanol till the ethanol content is 80-90 percent, standing for 24 hours, and filtering; 9, adding ethanol into filter residues till the ethanol content is 75-95 percent, standing for 18-30 hours, and filtering; 10, combining two filtrates, recovering ethanol, and concentrating under reduced pressure till the relative density is 1.15-1.30; 11, performing spray drying to obtain a honeysuckle flower extract; and 12, combining the baikal skullcap root extract with the honeysuckle flower extract, adding sodium bicarbonate to fixed amount, adding glucose to fixed amount, and mixing uniformly to obtain the honeysuckle flower-baikal skullcap root soluble powder.

Description

Technical field [0001] The invention relates to a high-purity silver-yellow soluble powder, and a preparation and quality detection method of the high-purity silver-yellow soluble powder. Background technique [0002] Yinhuang preparations are mainly composed of honeysuckle and scutellaria. It has the effects of clearing away heat, detoxifying, antibacterial and anti-inflammatory. It is one of the traditional medicines with a long history in my country. In the research and application at home and abroad, it has found its various pharmacological and clinical functions. Veterinarians are mainly used in livestock and poultry for exogenous fever, pneumonia, asthma and mixed infections caused by multiple bacteria. In addition, some data prove that its antibacterial and anti-inflammatory effects are significant, and it has obvious antibacterial effects on Proteus, Staphylococcus aureus, Staphylococcus aureus, Streptococcus A, and Streptococcus B; it also has a significant inhibitory eff...

AI Technical Summary

Problems solved by technology

[0004] Although there are many reports related to the preparation method of Yinhuang preparation, the method is more complicated and the cost is high, which is not conducive to popularization, development and application

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