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Chinese medicinal chrysanthemum buccal tablet

A buccal tablet and chrysanthemum technology, which is applied in the directions of antipyretics, drug combinations, pharmaceutical formulations, etc., can solve the problems of decreased main drug content, headaches for developers, taste problems, etc., and achieves less side effects, good therapeutic effects, and economical effect of time

Active Publication Date: 2013-05-22
ZHONGSHAN ZHONGZHI PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are also the following problems in the buccal tablets of traditional Chinese medicine: taste problems, and the feeling after the buccal tablets are taken in is often a headache for developers.
Stability issues, buccal tablets often cause changes in appearance due to moisture absorption and even a decrease in the content of the main drug

Method used

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  • Chinese medicinal chrysanthemum buccal tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Chrysanthemum 100g

[0051] Low-substituted hydroxypropyl cellulose 220g

[0052] Hydroxypropyl cellulose 20g

[0053] Micropowder silica gel 10g

[0054] Magnesium stearate 1g.

[0055] Take the chrysanthemum, pulverize it with a jet mill to make the particle size less than 50 μm, add fillers, binders, and glidants to mix and granulate, dry, sieve, add lubricant and directly compress to make 1000 tablets.

Embodiment 2

[0057] Chrysanthemum 100g

[0058] Low-substituted hydroxypropyl cellulose 150g

[0059] Hydroxypropyl cellulose 10g

[0060] Micropowder silica gel 1g

[0061] Magnesium stearate 0.1g.

[0062] Take the chrysanthemum, pulverize it with a jet mill to make the particle size less than 50 μm, add fillers, binders, and glidants to mix and granulate, dry, sieve, add lubricant and directly compress to make 1000 tablets.

Embodiment 3

[0064] Chrysanthemum 100g

[0065] Low-substituted hydroxypropyl cellulose 500g

[0066] Hydroxypropyl cellulose 40g

[0067] Micropowder silica gel 10g

[0068] Magnesium stearate 2g.

[0069] Take the chrysanthemum, pulverize it with a jet mill to make the particle size less than 50 μm, add fillers, binders, and glidants to mix and granulate, dry, sieve, add lubricant and directly compress to make 1000 tablets.

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Abstract

The invention relates to a Chinese medicinal chrysanthemum buccal tablet. 1000 buccal tablets of the invention are prepared by the following raw materials by weight: 100g of chrysanthemums, 1-500g of a filling agent, 1-40g of an adhesive, 1-10g of a glidant, and 0.1-2g of a lubricating agent.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine chrysanthemum buccal tablet. Background technique: [0002] Chrysanthemum is the dry flower head of Chrysanthemum chrysanthemum, which is a commonly used traditional Chinese medicine in my country. It has the effects of dispelling wind, clearing heat, improving eyesight and detoxifying. It mainly treats symptoms such as headache, dizziness, red eyes, dysphoria in the heart and chest, furunculosis, and swelling. Modern pharmacological studies have shown that chrysanthemum has various pharmacological activities such as treating coronary heart disease, lowering blood pressure, preventing hyperlipidemia, antibacterial, antiviral, anti-inflammatory, and anti-aging. Chrysanthemum is a homologous plant of medicine and food, and there are reports on its classification, identification, chemistry, clinical, pharmacology and other aspects at home...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/287A61P29/00A61P27/02A61P39/02A61P25/00A61P1/08A61P17/00A61P9/10A61P9/12A61P3/06
Inventor 成金乐陈金梅杨记宗苏观凤
Owner ZHONGSHAN ZHONGZHI PHARMA GRP
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