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Compound lightyellow sophora root-selinum japenious seed bacteriostatic lotion and preparation method thereof

A technology of cnidium and flavescens, applied in the field of compound flavescens cnidium antibacterial lotion and its preparation, can solve the problems of poor effect, high cost of raw materials, and destruction of active ingredients, and achieve protection of genital skin and mucous membranes with low cost , the effect of defense against bacterial invasion

Inactive Publication Date: 2012-07-04
上海豪源生物制品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to overcome defects such as high raw material cost and poor effect of the gynecological lotion in the prior art, and / or the preparation process destroys the active ingredients to cause poor effect, and provides a low-cost, Chinese and Western medicine Composition, compound flavescens cnidium antibacterial lotion with effective insecticidal, antipruritic, heat-clearing and damp-drying, detoxification and preparation method thereof

Method used

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  • Compound lightyellow sophora root-selinum japenious seed bacteriostatic lotion and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of extracts of Sophora flavescens, Cortex Phellodendri and Cnidium:

[0026] Take 70% ethanol by volume as the extraction solvent, heat reflux and extract flavescens, Phellodendron phellodendron and Fructus Cnidii (the weight ratio of medicinal materials 20%, 40%, 40%) for 3 times, each time for 1 hour, and the amount of ethanol is 6 times the amount of medicinal materials volume, combined extracts, filtered, the filtrate was vacuum decompressed to recover ethanol, and concentrated to a traditional Chinese medicine extract with a relative density of 1.08.

[0027] With the extract of 8% Sophora flavescens, Phellodendron Phellodendri and Fructus Cnidii, 0.3% chlorhexidine acetate, 0.7% dodecyl dimethyl amine oxide (surfactant OB-2), 25% ethanol, 0.1% borneol, make up The balance is 100% purified water, all ingredients are evenly mixed, and then filled.

[0028] The present embodiment product detects by the method specified in "Technical Standards for Disinfe...

Embodiment 2

[0030] Preparation of extracts of Sophora flavescens, Cortex Phellodendri and Cnidium:

[0031] With 50% ethanol by volume as the extraction solvent, flavescens, Cortex Phellodendri, and Fructus Cnidii (medicinal materials by weight ratio 10%, 45%, 45%) are heated and refluxed twice, each time for 1.5 hours, and the amount of ethanol is 8 times the quality of the medicinal materials Measure the volume, combine the extracts, filter, and vacuum the filtrate to recover ethanol, and concentrate to a traditional Chinese medicine extract with a relative density of 1.12.

[0032] 8% extracts of Sophora flavescens, Cortex Phellodendri and Fructus Cnidii, 0.25% chlorhexidine acetate, 0.8% fatty alcohol polyoxyethylene ether AEO-9, 30% ethanol, 0.1% menthol, make up the balance with 100% purified water, The ingredients are evenly mixed and filled.

[0033] The present embodiment product detects by the method specified in "Technical Standards for Disinfection" (Ministry of Health of the...

Embodiment 3

[0035] Preparation of extracts of Sophora flavescens, Cortex Phellodendri and Cnidium:

[0036] With 60% ethanol by volume as the extraction solvent, heat reflux to extract Sophora flavescens, Cortex Phellodendri, Fructus Cnidii (the weight ratio of medicinal materials is 25%, 35%, 40%) twice, each time is 1.5 hours, and the amount of ethanol is 7 times the quality of medicinal materials Measure the volume, combine the extracts, filter, and vacuum the filtrate to recover ethanol, and concentrate to a traditional Chinese medicine extract with a relative density of 1.10.

[0037] Take 9% extracts of Sophora flavescens, Cortex Phellodendri and Fructus Cnidii, 0.35% chlorhexidine acetate, 0.6% fatty alcohol polyoxyethylene ether LAE-9, 20% ethanol, make up the balance with 100% purified water, and mix the ingredients evenly. Just fill it.

[0038] The present embodiment product detects by the method specified in "Technical Standards for Disinfection" (Ministry of Health of the Pe...

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Abstract

The invention discloses a compound lightyellow sophora root-selinum japenious seed bacteriostatic lotion and a preparation method thereof. The lotion contains an extract of lightyellow sophora root, amur corktree bark and selinum japenious seed, chlorhexidine acetate, a surfactant, ethanol and water, wherein the surfactant is selected from lauryl dimethylamine oxide, Alcohol Ethoxylate (AEO-9), Lauric Acid Ethoxylate (LAE-9) and nonylphenol polyoxyethylene ether (NPE-10); the extract is prepared by performing reflux extraction on 10-25 percent of lightyellow sophora root, 35-45 percent of amur corktree bark and 35-45 percent of selinum japenious seed by taking 50-70 percent by volume of an ethanol aqueous solution as an extraction solvent for 1-3 times, every time for 1-1.5 hours, combining extracting solutions, filtering, recovering a filtrate under reduced pressure in vacuum, and concentrating with ethanol till the relative density is 1.08-1.12; and the using amount of the ethanol aqueous solution is 6-8 times of the total mass of the lightyellow sophora root, amur corktree bark and selinum japenious seed. The compound lotion consisting of Chinese native medicament and western medicament components has the effects of killing parasites to relieve itching, clearing heat, drying dampness and clearing away heat and toxic materials, can play a role in protecting private skin mucosa and preventing bacteria invasion, has low cost, and is suitable for young and middle-aged women.

Description

technical field [0001] The invention relates to a compound flavescens cnidium antibacterial lotion and a preparation method thereof. Background technique [0002] With the improvement of people's living standards, as well as the increase of life pressure and work pressure and the decrease of exercise, more and more women are in a sub-health state, mainly manifested in long-term use of sanitary pads, long-term sitting, or improper use of drugs, etc. Cause the body's immunity to decrease, the body's resistance to decrease, and then cause many gynecological diseases such as vulvitis, vaginitis, etc. The diseases that these old people suffer from begin to develop to the middle-aged and even young people. In response to this situation, a variety of products for the treatment of vaginitis and other gynecological diseases have appeared on the market, but the existing products are usually made of a variety of precious Chinese medicines, and the cost is very high, resulting in high ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P31/04A61P15/02A61P17/04A61P33/00A61K31/155
Inventor 李文峰
Owner 上海豪源生物制品有限公司
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