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Artificial blood vessel torsional fatigue simulating device for endovascular graft exclusion and testing method thereof

A technology of artificial blood vessels and simulation devices, which is applied in the direction of applying repeated force/pulsation force to test the strength of materials, etc., which can solve the problems of no torsional fatigue performance, blank and no retrieval of artificial blood vessel in vitro torsional fatigue simulation tests, etc., and achieve torsion resistance Good fatigue resistance, more reasonable and effective artificial blood vessel sample structure

Active Publication Date: 2014-04-16
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Through the review of a large number of documents and materials, it is found that although there have been relevant reports on the in vitro fatigue simulation of artificial blood vessels at home and abroad, the test on the in vitro torsional fatigue simulation of artificial blood vessels is still blank.
For example, the ELF9100 series vascular graft test system produced by the American Endura TEC company in foreign countries, the in vitro fatigue test system for artificial blood vessels designed by American scholars Pourdeyhimi et al. Using the artificial blood vessel wear resistance test device and the patent No. ZL 200710043812.4 textile artificial blood vessel fatigue performance simulation test device, etc., although the artificial blood vessel has been simulated in vitro, there is no test for the torsional fatigue performance
It is worth mentioning that the patent CN102175541A, which was published on September 7, 2011, is an artificial blood vessel in vitro simulation of bending fatigue aging device and its testing method. In terms of in vitro simulation of torsional fatigue aging of artificial blood vessels, there are currently no reports of relevant literature at home and abroad

Method used

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  • Artificial blood vessel torsional fatigue simulating device for endovascular graft exclusion and testing method thereof
  • Artificial blood vessel torsional fatigue simulating device for endovascular graft exclusion and testing method thereof
  • Artificial blood vessel torsional fatigue simulating device for endovascular graft exclusion and testing method thereof

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Experimental program
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Effect test

Embodiment 1

[0034] A test method for a torsional fatigue simulation device for an artificial blood vessel used in endovascular isolation described in this embodiment, the specific steps are as follows:

[0035] 1) Preparation of experimental materials: prepare a vertical hollow metal conduit 312 with a diameter of 6mm, an L-shaped hollow metal conduit 313" with a diameter of 6mm, a rack 310 with a length of 55mm, and a gear 311 with a diameter of 52mm, and prepare artificial blood vessel samples A and liner A 2 , the artificial blood vessel sample A adopts a straight tubular shape, and the fabric covering film A 1 Use polyester textile base, length L 1 70mm, diameter D 1 6mm, inner liner A 2 The material is made of silica gel, which is used together with artificial blood vessel sample A, and the inner liner tube A 2 lengthL 2 80mm, its diameter D 2 5mm, liner A 2 Set into the artificial blood vessel sample A fabric cover A 1 Inside, 5mm overhang at each end, fabric covered A ...

Embodiment 2

[0052] A test method for a torsional fatigue simulation device for an artificial blood vessel used in endovascular isolation described in this embodiment, the specific steps are as follows:

[0053] 1) Preparation of experimental materials: prepare a vertical hollow metal conduit 312 with a diameter of 15mm, an L-shaped hollow metal conduit 313" with a diameter of 15mm, a rack 310 with a length of 55mm, and a gear 311 with a diameter of 52mm, and prepare artificial blood vessel samples A and liner A 2 , the artificial blood vessel sample A adopts a straight tubular shape, and the fabric covering film A 1 Use polyester textile base, length L 1 70mm, diameter D 1 15mm, inner liner A 2 The material is made of silicone material, the length is L 2 80mm, diameter D 2 14mm, inner liner A 2 Set into the artificial blood vessel sample A fabric cover A 1 Inside, 5mm overhang at each end, fabric covered A 1 Upper suture A 3 Suture has 3 independent metal brackets A 4 , the sutu...

Embodiment 3

[0071] A test method for a torsional fatigue simulation device for an artificial blood vessel used in endovascular isolation described in this embodiment, the specific steps are as follows:

[0072] 1) Preparation of experimental materials: prepare a vertical hollow metal conduit 312 with a diameter of 30mm, a horizontal hollow metal conduit 313' with a diameter of 30mm, a rack 310 with a length of 55mm, a gear 311 with a diameter of 52mm, and prepare artificial blood vessel sample A and liner A 2 , the artificial blood vessel sample A adopts a straight tubular shape, and the fabric covering film A 1 Use polyester textile base, length L 1 215mm, diameter D 1 30mm, inner liner A 2 The material is made of silicone material, the length is L 2 225mm, diameter D 2 29mm, inner liner A 2 Set into the artificial blood vessel sample A fabric cover A 1 Inside, 5mm overhang at each end, fabric covered A 1 Upper suture A 3 Suture has 3 independent metal brackets A 4 , the su...

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Abstract

The invention relates to an artificial blood vessel torsional fatigue simulating device for endovascular graft exclusion and a testing method thereof. The device comprises a liquid storage box, an electronic peristaltic pump, a pressure monitor, a current limiter and a flow guide silicone tube; and the device is characterized by further comprising an artificial blood vessel torsion simulating device. The invention further discloses a testing method using the device. By using the method, the in vivo torsion motion of the artificial blood vessel is simulated through the engagement between a rack and a gear which rotate in a horizontal way; the artificial blood vessel test sample is simulated in different in vivo positions through a horizontal or L-shaped hollow metal conduit; and factors affecting the torsional fatigue resistance of the artificial blood vessel are obtained through comparison test of the artificial blood vessels with different structures. By using the artificial blood vessel torsional fatigue simulating device for endovascular graft exclusion, provided by the invention, a gap in the traditional vitro simulation of the artificial blood vessel torsional fatigue for endovascular graft exclusion is filled and more scientific basis is provided for completing the structure of the artificial blood vessel.

Description

technical field [0001] The invention relates to an artificial blood vessel torsion fatigue simulation device for intracavity isolation and a testing method thereof, belonging to the field of biomedical textiles. Background technique [0002] Thoracoabdominal aortic hemangioma is a common clinical disease, and endovascular exclusion, as an effective technique for the treatment of thoracoabdominal aortic aneurysm, has been adopted by more and more hospitals. Endovascular exclusion uses artificial blood vessels as the key technology of treatment, and its fatigue performance evaluation is particularly important. Among them, in vitro simulation is one of the most effective means to evaluate the fatigue performance of artificial blood vessels. Through a large number of follow-up investigations and studies on artificial blood vessel grafts used in the clinical treatment of thoracic aortic aneurysms, it was found that in the cases of clinical failure of thoracotomy, the artificial b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N3/36
Inventor 王璐刘冰林婧王富军关国平金.马汀
Owner DONGHUA UNIV