Film-covered stent

A stent-covered and film-covered technology, applied in medical science, surgery, etc., can solve problems such as thrombosis and intimal hyperplasia, and achieve the effect of inhibiting endothelial cell proliferation and smooth muscle cell proliferation.

Inactive Publication Date: 2012-07-18
BEIHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the problems existing in the prior art, the present invention proposes a new covered stent to solve the problems of thrombus and intimal hyperplasia caused by the bare stent at the end of the covered stent

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] specific implementation plan

[0012] Specific embodiments of the present invention are described as follows:

[0013] For the covered stent with an uncoated part at the end, the uncoated part is treated with drug coating during the production process, and the drug coating method is the same as the drug coating method for the vascular interventional drug-coated stent. The drugs used are mainly anti-platelet, anti-coagulant, anti-endothelial cell proliferation, and anti-smooth muscle cell proliferation drugs, specifically statins, rapamycins, paclitaxel, and heparin drugs. A combination of 2-4 types.

[0014] Through the above design, it is possible to prevent the uncoated part at the end of the stent graft from causing thrombus and intimal hyperplasia near the end of the stent graft. In addition, because the ungrafted portion of the covered stent usually blocks the entrance of the bifurcated vessel. Therefore, after the uncoated part is designed as a drug-coated sten...

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PUM

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Abstract

The invention discloses a film-covered stent. Usually, the end of the film-covered stent is provided with a part which is not covered by a film, so that the film-covered stent is well anchored, and an inlet of a branched blood vessel is prevented from being shaded. But thrombus, intimal hyperplasia and the like are easily caused by the part which is not covered by the film, the stability of blood flow in the branched blood vessel can be interfered, and stenosis is caused in the branched blood vessel. In order to solve the problems, the invention provides a new design scheme of the film-covered stent. The part which is not covered by the film and arranged at the end of the film-covered stent is a drug eluting stent, and a drug eluting method is the same as that of the ordinary drug eluting stent.

Description

technical field [0001] The invention relates to a covered stent Background technique [0002] Abdominal aortic aneurysm (AAA) is a dilated bulge in the wall of the abdominal aorta. The prevalence of abdominal aortic aneurysm accounts for 63%-79% of aortic aneurysms, and it mostly occurs in the elderly over 60 years old. It is like a time bomb in the body, once it bursts, the mortality rate is extremely high. At present, endovascular aneurysm repair (EVAR) is widely used clinically to treat abdominal aortic aneurysm. Early stent-graft repair had relatively strict restrictions on the shape of abdominal aortic aneurysms. In order to achieve effective attachment of the proximal end of the stent-graft and prevent migration and endoleak of the stent-graft, the abdominal aorta The distance between the proximal end of the tumor and the bifurcation of the renal artery should be greater than 15-20mm. However, clinically, about 30% to 40% of patients do not meet this requirement an...

Claims

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Application Information

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IPC IPC(8): A61B17/12A61L31/16
Inventor 孙安强邓小燕樊瑜波刘肖占帆王振泽
Owner BEIHANG UNIV
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