Amnion-based biological material and preparation method and uses thereof

A technology of biomaterials and amniotic membranes, applied in medical science, prosthesis, surgery, etc., to promote the differentiation of goblet cells, facilitate preparation, and reduce scar formation
CN102631707AInactive Publication Date: 2012-08-15XIAMEN UNIV
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Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
XIAMEN UNIV
Publication Date
2012-08-15
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

The invention relates to an amnion-based biological material and a preparation method and uses thereof, and relates to a biological material. The amnion-based biological material is a de-epithelialized amniotic tissue. The preparation method of the amnion-based biological material i.e. the de-epithelialized amniotic tissue comprises the following steps that: the amniotic tissue is de-epithelialized to remove amniotic epithelial cells so as to obtain the amnion-based biological material. The amnion-based biological material can be used as a mucosal epidermis repair promoting material or epithelial cell repair promoting material so as to promote the tissue reconstruction of the ocular surface, the oral cavity, the respiratory tract, the stomach and the vaginal mucosal. The implementation process is safe, reliable and easy. The source of amnion is wide, and the de-epithelialized amnion can be conveniently prepared. The amnion transplant surgery is simple to operate and easy to implement.
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Description

technical field

[0001] The invention relates to a biological material, in particular to a biological material based on amniotic membrane and its preparation method and application. Background technique

[0002] There are a large number of ocular surface epithelial injury diseases in clinical ophthalmology: such as: ocular chemical injury, eye thermal burn, etc.; Corneal chronic inflammatory diseases caused by etiology, whether it is a large-scale epithelial cell defect, or a systemic disease caused by epithelial cell defect, the protracted chronic course of the disease can lead to corneal ulcers or cicatricial changes, symblepharonitis Even serious consequences such as blindness. Since scholars introduced intact amniotic membrane into ophthalmology clinical treatment in the 1990s, basic and clinical research on amniotic membrane has been gradually carried out. So far, intact amniotic membrane has been proven to promote the repair of epithelial cells, and has anti-inflammat...

Claims

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