Quality analysis data processing method and quality analysis data processing system

Abstract

Provided is a method for quickly obtaining an intensity value at a desired m / z value in a compressed data obtained by run-length encoding of a mass analysis data. An index is created by pairing either the start position of a section where zero-intensity consecutively occurs two or more times in an array of an original spectrum data, or the start position of a sequence of data having significant intensity values in an array of the original spectrum data, with the corresponding position in an array of a compressed data. This index is stored separate from the compressed data. The creation of the index does not affect the array of the compressed data. Therefore, the data can be decompressed even by a data processing system that does not use the index. The index helps to quickly locate a compressed data corresponding to the desired m / z and obtain the necessary intensity value.

Description

technical field

[0001] The present invention relates to a method for processing data collected by mass analysis, and in particular to an image adapted to be able to acquire an image showing the distribution of signal intensities of a specific mass-to-charge ratio within a two-dimensional area on a sample ( Hereinafter, this image will be referred to as a "mass analysis result image") in the data processing method of the imaging mass spectrometer. The invention also relates to a mass spectrometer using this method. Background technique

[0002] Mass spectrometry imaging is a technique for studying the distribution of a substance having a specified mass-to-charge ratio (m / z) by performing mass analysis on a plurality of minute regions within a two-dimensional region of a sample such as a piece of biological tissue, respectively. This technology is expected to be used, for example, in drug discovery, biomarker discovery, and etiological investigation of various diseases. Mass...

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