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Application of aliphatic amine polymer, as well as medicinal composition and preparation method thereof

A technology of aliphatic amine polymers and compositions, applied in the field of medicine, can solve problems such as the use of sevelamer, and achieve the effects of preventing the formation of lipofuscin, reducing blood lipids, and preventing peroxidation

Inactive Publication Date: 2014-06-04
NEW FOUNDER HLDG DEV LLC +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, there is no use of Sevelamer in reducing fat and losing weight in the prior art

Method used

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  • Application of aliphatic amine polymer, as well as medicinal composition and preparation method thereof
  • Application of aliphatic amine polymer, as well as medicinal composition and preparation method thereof
  • Application of aliphatic amine polymer, as well as medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Prepare the medicine for acquired obesity with Sevelamer Hydrochloride and the following auxiliary materials, Sevelamer Hydrochloride 3g / bag, prepare 1000 bags.

[0055] prescription

[0056]

[0057] Preparation method: Weigh the prescribed amount of sevelamer hydrochloride and other auxiliary materials and mix evenly, add appropriate amount of starch slurry to make a soft material according to the conventional method, pass through a 60-mesh sieve, dry at 65°C for 3 hours, prepare granules, and put them into aluminum foil bags , that is, a medicine that can be orally treated for acquired obesity.

Embodiment 2

[0059] The ratio of Sevelamer hydrochloride and vitamin E is 67:1, Sevelamer hydrochloride is 3g / bag, and 1000 bags are prepared.

[0060] prescription

[0061]

[0062] Preparation method: Weigh the prescribed amount of vitamin E, absorb it with silicon dioxide, mix it with sevelamer hydrochloride and other auxiliary materials, add appropriate amount of starch slurry according to the conventional method to make a soft material, pass through a 60-mesh sieve, and dry at 65°C for 3 hour, prepare granules, put them into aluminum foil bags, and obtain the medicine for oral treatment of acquired obesity.

Embodiment 3

[0064] The ratio of sevelamer carbonate and vitamin E is 67:1, 1 g / bag of sevelamer carbonate, and 1000 bags are prepared.

[0065] prescription

[0066]

[0067] Preparation method: Weigh the prescribed amount of vitamin E, absorb it with silicon dioxide, mix it with sevelamer carbonate and other auxiliary materials, add appropriate amount of starch slurry according to the conventional method to make a soft material, pass through a 60-mesh sieve, and dry at 75°C for 2 hour, prepare granules, put them into aluminum foil bags, and obtain the medicine for oral treatment of acquired obesity.

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Abstract

The invention provides application of aliphatic amine polymer, as well as a medicinal composition and a preparation method thereof. The medicinal composition comprises a) aliphatic amine polymer and b) fat-soluble vitamin, wherein the fat-soluble vitamin is one or more than one of fat-soluble vitamin A, D, E and K. The invention also provides a preparation method of the medicinal composition. The medicinal composition plays roles in reducing blood fat and reducing weight, and can be used for maintain the level of fat-soluble vitamin.

Description

technical field [0001] The invention relates to the technical field of medicine. In particular, it relates to a weight-reducing and anti-oxidation pharmaceutical composition made of aliphatic amine polymers (especially Sevelamer) and vitamins (especially vitamin E) and a preparation method. Background technique [0002] With the development of society and the improvement of people's living standards, acquired obesity caused by eating too much or reducing exercise in adults has become a common phenomenon. However, people's desire to pursue beauty and health has always been very strong. Therefore various weight-loss drugs arise at the historic moment, and when losing weight, many adverse reactions can be produced to the body. The most common weight-loss drugs currently on the market mainly contain three categories: one is an appetite suppressant, the other is an agent that accelerates metabolism and reduces absorption, and the other is a preparation that helps consume fat an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/785A61K31/355A61P3/04A61P39/06A61P17/18
Inventor 郭欲晓徐环昕易崇勤王振国丁继军李劲任爱国
Owner NEW FOUNDER HLDG DEV LLC
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