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Application of pharmaceutical composition in preparing medicines used for preventing and treating diabetic cardiomyopathy

A technology of diabetic cardiomyopathy and composition, which is applied in the application field of pharmaceutical composition in the preparation of drugs for preventing and treating diabetic cardiomyopathy, and can solve problems such as the role of pharmaceutical composition in preventing and treating diabetic cardiomyopathy

Active Publication Date: 2012-12-12
GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0017] However, neither the patent nor related documents mentioned that the pharmaceutical composition has the effect of preventing and treating diabetic cardiomyopathy.

Method used

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  • Application of pharmaceutical composition in preparing medicines used for preventing and treating diabetic cardiomyopathy
  • Application of pharmaceutical composition in preparing medicines used for preventing and treating diabetic cardiomyopathy
  • Application of pharmaceutical composition in preparing medicines used for preventing and treating diabetic cardiomyopathy

Examples

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Embodiment Construction

[0026] In order to clarify the curative effect of pharmaceutical composition of the present invention for the treatment of diabetic cardiomyopathy, the present invention will be further elaborated by the following examples:

[0027] 1. Experimental samples:

[0028]1.1 Sample name: Xiaoke Pill A, which is the pharmaceutical composition of the present invention, preparation method: refer to the preparation method of "Chinese Pharmacopoeia" 2010 edition Xiaoke Pill, according to the weight ratio of the pharmaceutical composition of the present invention, that is, Rehmannia glutinosa 636 parts by weight, Radix Astragalus 212 parts by weight, 106 parts by weight of Chinese yam, 1060 parts by weight of kudzu root, 1060 parts by weight of trichosanthin, 1060 parts by weight of corn silk, and 212 parts by weight of Schisandra chinensis. Add Pueraria root, rehmannia glutinosa, corn silk and trichosanthemi to decoct for 5 hours, filter, and concentrate the filtrate to an appropriate am...

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Abstract

The invention discloses an application of a pharmaceutical composition in preparing medicines used for preventing and treating diabetic cardiomyopathy. The active component of the pharmaceutical composition is mainly prepared from the medicine materials of: rehmannia, Mongolian milkvetch root, common yam rhizome, lobed kudzuvine root, snakegourd root, corn stigma, and kadsura japonica. With other currently known oral hypoglycemic western medicines such as glibenclamide or metformin, the pharmaceutical composition can be prepared into oral composite preparations used for preventing and treating diabetic cardiomyopathy.

Description

technical field [0001] The invention relates to a new application of a pharmaceutical composition, in particular to an application of a pharmaceutical composition in the preparation of medicines for preventing and treating diabetic cardiomyopathy. Background technique [0002] Diabetic cardiomyopathy is one of the main complications of diabetes. It refers to a disease state in which the primary damage of cardiomyocytes in diabetic patients causes extensive structural abnormalities, and eventually causes ventricular hypertrophy, diastolic and / or systolic dysfunction. Rubler (Rubler) was first proposed in 1972. In recent years, a large number of studies have confirmed that diabetic cardiomyopathy is an independent pathophysiological state, microvascular disease is one of the important reasons for the occurrence and development of diabetic cardiomyopathy, and its occurrence has nothing to do with coronary artery blood supply disorder. The main clinical manifestation is congest...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K45/06A61P3/10A61P9/00A61K31/64
Inventor 刘菊妍吴长海周凤娇周杰邓慧敏杨威肖百全赖晓明卢素红项磊
Owner GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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