Tilianin microemulsion composition
A technology of microemulsion and composition, which is applied in the field of tianjirin microemulsion composition, can solve the problems of increasing solubility, restricting the effective development and utilization of preparations, etc., and achieves the effect of simple preparation method
Inactive Publication Date: 2014-08-20
石河子大学医学院第一附属医院
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- Abstract
- Description
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AI Technical Summary
Problems solved by technology
Poor water-solubility of stianinin limits the effective development and utilization of its formulations
[0003] The Chinese patent announcement number is CN10178345A discloses the preparation method of stellin, but, the shortcoming of this method is, does not provide a kind of increase to meet the requirement of preparation for the disclosed stellin according to the water-insoluble property. Solubility method
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 1
[0011] Stellin: 0.2 parts, polyoxyethylene hydrogenated castor oil: 5 parts, polyethylene glycol-400: 10 parts, isopropyl myristate: 10 parts, water: 30 parts
Embodiment 2
[0013] Stellin: 0.2 parts, lecithin: 9 parts, ethanol: 9 parts, ethyl oleate: 10 parts, water: 20 parts
Embodiment 3
[0015] Tianjiin: 0.4 parts, Tween-80: 10 parts, Propylene Glycol: 5 parts, Ethyl Oleate: 10 parts, Water: 10 parts
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Abstract
The invention discloses a microemulsion composition containing tilianin. The microemulsion composition comprises tilianin, an emulsifier, a co-emulsifier, oil and water. The microemulsion composition can greatly enhance the solubility of the tlianin.
Description
technical field [0001] The invention relates to a stellin microemulsion composition capable of significantly increasing the solubility of scinnamon. Background technique [0002] Tintin is an important flavonoid glycoside compound extracted from the Lamiaceae plant Cymbidium chinensis, which has biological activities such as anti-atherosclerosis, anti-hypertension, and myocardial protection. Stinin is a weak acid drug, insoluble in water, easily soluble in acetonitrile, dimethyl sulfoxide, methanol, chloroform, ethyl acetate and other organic solvents. The poor water solubility of stellin limits the effective development and utilization of its preparations. [0003] The Chinese patent announcement number is CN10178345A discloses the preparation method of stellin, but, the shortcoming of this method is, does not provide a kind of increase to meet the requirement of preparation for the disclosed stellin according to the insoluble property of stellin Solubility method. Cont...
Claims
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/107A61K31/7048A61K47/44A61K47/24A61K47/34A61P9/10A61P9/12
Inventor 王新春邢建国袁勇韩博李静王晓义
Owner 石河子大学医学院第一附属医院
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