Preparation method of traditional Chinese medicine particles for treating cold and influenza

A technology of traditional Chinese medicine granules and influenza, applied in the field of medicine, can solve the problems of lack of effective control of extract quality, affecting the dissolution of active ingredients, loss of heat-sensitive components of drugs, etc., to save production time, shorten heating time, and reduce degradation and loss. Effect

Inactive Publication Date: 2013-02-27
JIANGXI POZIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the high decoction temperature and long decoction time, this method is time-consuming, labor-intensive, and energy-intensive, and is likely to cause serious loss of heat-sensitive components of the drug and thus affect the efficacy of the drug; and licorice has many fibers, and it is difficult to completely pulverize it into fine powder by conventional pulverization. Powder, which affects the dissolution of active ingredients; at the same time, there is no effective control on the quality of the extract, which is extremely incompatible with the modernization requirements of traditional Chinese medicine preparation technology

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Weigh 625g of isatidis root, 750g of goldenrod, 1000g of a little red, 375g of licorice, and 63g of ginger. Wherein the licorice is ultrafinely pulverized to obtain the licorice fine powder passed through a 200-mesh sieve. Add 8 times the amount of water to Banlangen, use 400w microwave heating to extract twice, each time for 15 minutes, the obtained extracts are combined and filtered, the filtrate is concentrated to a relative density of 1.10 (50°C), and ethanol is added to make the alcohol content reach 60% , filtered, and the filtrate was concentrated to a relative density of 1.10 (50° C.) after recovering ethanol to obtain Banlangenqing paste. Add 10 times the amount of water to goldenrod, a little red, and ginger, and use 400w microwave heating to extract twice, 15 minutes each time. The obtained extracts are combined and allowed to stand for 12 hours. The supernatant is concentrated to a relative density of 1.10 (50°C ), to obtain the water extract clear ointment...

Embodiment 2

[0016] Weigh 625g of isatidis root, 750g of goldenrod, 1000g of a little red, 375g of licorice, and 63g of ginger. Wherein the licorice is ultrafinely pulverized to obtain licorice fine powder passing through a 300-mesh sieve. Add 8 times the amount of water to Banlangen, use 600w microwave heating to extract twice, 10 minutes each time, the obtained extracts are combined and filtered, the filtrate is concentrated to a relative density of 1.15 (50°C), and ethanol is added to make the alcohol content reach 60% , filtered, and the filtrate was concentrated to a relative density of 1.15 (50° C.) after recovering ethanol to obtain Banlangenqing paste. Add 10 times the amount of water to goldenrod, a little red, and ginger, and use 600w microwave heating to extract twice, 10 minutes each time. The obtained extracts are combined and allowed to stand for 18 hours, and the supernatant is concentrated to a relative density of 1.15 (50°C ), to obtain the water extract clear ointment. ...

Embodiment 3

[0018] Weigh 2.7kg Radix Radix, 3kg Solidago, 4kg Radix Glycyrrhizae, 1.5kg Radix Glycyrrhizae, and 0.25kg Ginger. Wherein the licorice is ultrafinely pulverized to obtain the licorice fine powder passed through a 200-mesh sieve. Add 8 times the amount of water to Banlangen, use 600w microwave heating to extract twice, each time for 20 minutes, the obtained extracts are combined and filtered, the filtrate is concentrated to a relative density of 1.15 (50°C), and ethanol is added to make the alcohol content reach 75% , filtered, and the filtrate was concentrated to a relative density of 1.10 (50° C.) after recovering ethanol to obtain Banlangenqing paste. Add 10 times the amount of water to goldenrod, a little red, and ginger, and use 600w microwave heating to extract twice, 20 minutes each time. The obtained extracts are combined and allowed to stand for 24 hours, and the supernatant is concentrated to a relative density of 1.10 (50°C ), to obtain the water extract clear oint...

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Abstract

The invention discloses a preparation method of traditional Chinese medicine particles for treating cold and influenza and belongs to the technical field of medicines. The preparation method comprises that isatis root, solidago decurrens, emilia sonchifolia, liquorice root and fresh ginger are subjected to superfine grinding, microwave heating extraction, alcohol precipitation, microwave extraction, standing, microfiltration membrane filtration, condensation and granulation. The preparation method has a short production period, short heating time, a high yield and less impurities, saves production time, improves an extraction ratio, reduces degradation and a loss of thermosensitive ingredients in a drug, reduces impurity content, simplifies extraction processes, reduces a production cost and improves product quality.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a preparation method of traditional Chinese medicine granules for treating cold and flu. Background technique [0002] Cold is a kind of commonly encountered diseases and frequently-occurring disease, and cold medicine is the standing medicine of family. The therapeutic effect of western medicine on cold is not obvious, and most of them play the role of improving symptoms, while the effect of traditional Chinese medicine on cold is more obvious. Traditional Chinese medicine granules used to treat colds and flu are widely used clinically in the treatment of colds, and the curative effect is remarkable. The Chinese patent application with the publication number CN1887339A discloses a preparation method of Ganmaoyankeling. The product made by the preparation method is sugar-free granules, so it has a quicker effect than tablets; it is more suitable than syrups. It is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/16A61P11/00A61P31/16
Inventor 肖军平吴永忠康兴东余宝平李旭
Owner JIANGXI POZIN PHARMA
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