Tannic acid preparation for treating burn, bedsore and diaper dermatitis and preparation method thereof
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of preparation and tannin, applied in the field of tannin preparation and preparation
Inactive Publication Date: 2013-04-17
XINXIANG MEDICAL UNIV
View PDF0 Cites 7 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
[0003]Because tannic acid is a hydrolyzed tannin, a large amount of tannic acid absorbed into the body will damage the liver, so tannic acid is often made into external preparations for clinical use, such as tannic acid ointment It can precipitate protein, has astringent effect, hardens the skin, thereby protecting the mucous membrane, preventing excessive secretion and hemostasis, and can reduce local pain, reduce plasma exudation at the injured area, and prevent bacterial infection. It can be used to treat burns, eczema, Bed sores and diaper dermatitis (red buttocks of newborns), but the tannic acid ointment made by the previous method often has uneven dispersion of tannic acid, coarse particles, easy oxidative discoloration, matrix stratification is easy to occur during storage, and it is often applied in clinical use Unevenness reduces the effective contact area between tannic acid and the skin, which directly affects the effect of the drug
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0019] 1. Prescription for tannic acid ointment:
[0020] raw material Prescription amount Tannic acid 50g glycerin 50g sodium bisulfite 1g Glyceryl monostearate 120g beeswax 50g paraffin 50g Yellow Vaseline 50g liquid paraffin 250g Span 80 20g Tween 80 10g Ethylparaben 2g water Add to 1000g
[0021] 2. Preparation of tannic acid ointment:
[0022] Dissolve tannic acid with a small amount of ethanol or water, and then mix it with glycerin to obtain tannic acid glycerol solution. Glyceryl monostearate, beeswax, paraffin, yellow petrolatum, liquid paraffin and Span 80 were heated to 70°C, and stirred evenly to obtain an oil phase. The glycerol tannin solution, Tween 80, ethylparaben and water were heated to 70°C and stirred evenly to obtain an aqueous phase. Add the water phase to the oil phase, stir evenly while adding, condense and separate to obtain tannic acid ointment.
[0023] 3...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention relates to a tannic acid preparation and a preparation method, and the tannic acid preparation is characterized by comprising, by weight, 2-30% of tannic acid, 40-75% of pharmaceutical adjuvants, and 20-50% of water. The pharmaceutical adjuvants used in the preparation comprise glycerin, monoglyceride stearate, beeswax, Vaseline, paraffin, tween, span, sodium bisulfate, ethylparaben, etc. The preparation method comprises the following steps: dissolving tannic acid by a little water or ethanol, heating to 55-85 DEG C to prepare an oil phase and a water phase, finally adding the water phase into the oil phase under uniform stirring, and performing condensation and split charging to obtain the tannic acid preparation. The preparation comprises paste agents (ointment, plaster), cream, emulsion, oil agents, water aqua, and the like, and the tannic acid content can be determined by a spectrophotometric method. The prepared tannic acid preparation conforms with medicine standards, and is suitable for the treatment of burn, bedsore and diaper dermatitis (neonatal red buttock) and the like.
Description
technical field [0001] The invention relates to a tannic acid preparation and a preparation method thereof, which meet the drug standards and are mainly used for treating burns, bedsores, diaper dermatitis and other diseases, and belong to the field of biomedicine. Background technique [0002] Tannin (Gallotannin, Tannin), also known as tannin, tannin, tannin, diplic acid, larch extract, gallin tannin, tannin, carnic acid, soft acid, molecular weight 1701.20, melting point: 210~215℃, slight special smell, strong astringent taste, darken when exposed to light and air, soluble in water, easily soluble in ethanol, acetone and glycerin, almost insoluble in ether, benzene, chloroform and petroleum ether. Tannic acid can precipitate proteins, and can form insoluble complexes with alkaloids, glycosides and heavy metals. Inflammation and other diseases, and gastric lavage with its solution has detoxification effect on dehydrated morphine, gentian, digitalis, lead, silver, copper, ...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.