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Drug for curing vasogenic cerebral edema

A brain edema and drug technology, applied in the field of drugs for the treatment of vasogenic cerebral edema, can solve the problems of induced cerebral hemorrhage, automatic regulation dysfunction, and poor control of safe doses of quick-acting drugs, etc., to prevent epilepsy and strong walking ability Effect

Inactive Publication Date: 2014-04-16
吴林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above treatment regimens have the following defects in the treatment of vasogenic cerebral edema: ①The course of vasogenic cerebral edema is not consistent with Qi stagnation, blood stasis, and hyperactivity of liver-yang; Rapidly reduce the intracranial pressure. At this time, if you use drugs for promoting blood circulation and removing blood stasis, extinguishing wind and relieving convulsions, or removing dampness, they will actually overlap with the effects of western medicines, making it difficult to control the safe dose of quick-acting drugs and induce cerebral hemorrhage; ④ Vasogenic cerebral edema is related to the dysfunction of autoregulation of cerebral circulation, which has not been paid attention to by Western medicine and traditional Chinese medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1, the weight ratio of raw materials: loofah 10g, August berry 8g, stamen 8g, chrysanthemum 6g, senecio 6g, pangolin 8g, tallow 6g, cassia twig 3g, stone gallbladder 3g.

Embodiment 2

[0029] Example 2, raw material drug weight ratio: loofah 20g, August Zha 15g, stamen 15g, chrysanthemum 10g, Senecio 10g, pangolin 15g, tallow 10g, cassia twig 6g, stone gallbladder 6g.

Embodiment 3

[0030] Example 3, the weight ratio of raw materials: loofah 15g, August Zha 10g, stamen 10g, Chonglou 8g, Senecio 8g, pangolin 10g, tallow 8g, cassia twig 5g, stone gallbladder 5g.

[0031] When in use, add water to decoct the traditional Chinese medicine loofah of the present invention, August Zha, stamens, Chonglou, Senecio, Pangolin, Sapium sylvestris, stone gallbladder, and cassia twig, and combine the filtrates, and take it in the morning and evening. Or make dosage forms such as oral liquid and use.

[0032] The effective combination and coordination of the above drugs can effectively achieve the purpose of treating vasogenic cerebral edema with less side effects. The above results are fully proved by the clinical data, and the relevant data are as follows, wherein the drug used in the study is the weight ratio of the bulk drug in Example 3.

[0033] 1 Objects and methods.

[0034] 1.1 Objects: 42 patients with vasogenic cerebral edema diagnosed between January 2009 an...

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PUM

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Abstract

The invention discloses a drug for curing vasogenic cerebral edema to solve the problem of curing vasogenic cerebral edema. The drug is characterized by being prepared and processed from various Chinese medicinal herbs, and raw materials filling a prescription and proportioned by weight are as follows: 10-20 parts of loofah sponge, 8-15 parts of fiveleaf akebia fruit, 8-15 parts of marmor serpentinatum, 6-10 parts of paris polyphylla, 6-10 parts of groundsel, 8-15 parts of manis pentadactyla, 6-10 parts of kerr treebine roots and stems, 3-6 parts of cassia twig and 3-6 parts of chalcanthite. Clinical experiment proves that the drug for curing vasogenic cerebral edema has the characteristics of excellent curative effect and higher safety, and deserves clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a medicine for treating vasogenic cerebral edema. Background technique [0002] Vasogenic cerebral edema is the most common type of cerebral edema, secondary to disruption of the blood-brain barrier due to increased permeability of cerebral vessels. Its characteristics are: the blood-brain barrier in the lesion area is damaged, and the vascular permeability increases; the water, Na+, and Clˉ content of the tissue increase at the same time as the edema, and the increased vascular permeability mainly occurs in the capillary endothelial cells and the tight antibody junctions of the endothelial cells department. This type of edema is common in brain tumors (especially brain metastases, malignant gliomas), brain abscesses, cerebrovascular accidents, brain trauma and other diseases. In terms of brain compression symptoms, cerebral edema plays a more important role than the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/87A61K36/896A61P25/00A61P7/10A61K35/36A61K33/34A61K33/10
Inventor 吴林
Owner 吴林