Medicine for treating acute glomerulonephritis (AGN) hypertensive crisis

Abstract

The invention discloses a medicine for treating acute glomerulonephritis (AGN) hypertensive crisis to solve the problem of treatment of AGN hypertensive crisis. The medicine is characterized by being prepared from the following raw materials in parts by weight: 10-20 parts of luffa vegetable sponge, 8-15 parts of herba cladostachvdis, 8-15 parts of herba sarcandrae, 6-10 parts of paris polyphylla, 6-10 parts of pawpaw, 8-15 parts of China dodder, 6-10 parts of Chinese tallowtree root-bark, 3-6 parts of cassia twig and 3-6 parts of stone ball. Clinical experiments prove that the medicine has the characteristics of good curative effect on AGN hypertensive crisis and higher safety, and deserves clinical application and promotion.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a medicine for treating acute glomerulonephritis hypertensive crisis. Background technique [0002] Acute glomerulonephritis (AGN), referred to as acute nephritis, is mostly an immune complex disease that causes the body to produce an autoimmune response after streptococcal infection. AGN is more common in children or young people, and it is more common in 5-20 years old. Before the onset, most patients had a history of streptococcal infection and viral infection, often accompanied by fever, edema, and hematuria. In severe cases, heart failure or hypertensive encephalopathy may occur. [0003] Acute glomerulonephritis hypertensive crisis, that is, acute glomerulonephritis is complicated by acute glomerulonephritis in a short period of time when blood pressure increases sharply, resulting in cerebral vasoconstriction, resulting in cerebral ischemia, and severe increas...

AI Technical Summary

Problems solved by technology

However, the above treatment regimens have the following defects in the treatment of AGN hypertensive crisis: ① AGN hypertensive crisis is not consistent with the course of hypertension, and AGN hypertensive crisis is secondary to the primary disease of acute glomerulonephritis; ② AGN hypertensive crisis The pathogenesis of AGN hypertensive crisis is different from that of hypertension. In the early stage of AGN hypertensive crisis, cerebral vasoconstriction produces cerebral ischemia, and in the later stage, the severe increase of blood pressure makes the automatic regulation of cerebral circulation dysfunction. In some cases, the degree of cerebral edema is not parallel to blood pressure; ③ as It is a kind of hypertensive emergency. The clinical treatment usually adopts rapid venous access and fast-acting drugs to quickly reduce blood pressure. At this time, if Pinggan Xifeng is used to relieve convulsions, it is actually superimposed with the drug effect of western medicine, making sodium nitroprusside Or the safe dosage of fast-acting drugs such as alphonat is more difficult to control, which will cause renal blood perfusion disorder and induce acute renal failure; ④AGN hypertensive crisis is related to the dysfunction of cerebral circulation autoregulation, Western medicine and traditional Chinese medicine treatment didn't pay attention to this