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Application of hedan preparation in preparation of diabetes medicine

A kind of diabetes drug and diabetes technology, applied in the direction of drug combination, pharmaceutical formula, metabolic diseases, etc.

Active Publication Date: 2013-07-10
NANCHANG JISHUN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hypoglycemic effect of western medicine is affirmative, but its adverse reactions are also obvious to all

Method used

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  • Application of hedan preparation in preparation of diabetes medicine
  • Application of hedan preparation in preparation of diabetes medicine
  • Application of hedan preparation in preparation of diabetes medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115] The medicine of the present invention is made up of the following components

[0116] Lotus leaf: 7500g Salvia: 1250g Hawthorn: 3750g Senna leaf: 375g Psoralen: 1250g

[0117] For the above five flavors, senna leaves were soaked in hot water at 90°C for three times, 30 minutes each time, combined soaking liquid, filtered, and the filtrate was used for later use; Danshen was crushed into coarse powder, heated and refluxed with ethanol for 1.5 hours, filtered, and the ethanol was recovered from the filtrate. Reserve; decoct lotus leaf, psoraleae, hawthorn and Danshen dregs with water twice, 2 hours each time, filter the decoction, combine the filtrates, concentrate under reduced pressure to a relative density of 1.20 (60°C), place, and wait for medicine When the liquid temperature drops to about 40°C, add 2 times the amount of ethanol, stir well, let it stand for 48 hours, take the supernatant, filter, recover ethanol from the filtrate, combine with the above-mentioned et...

Embodiment 2

[0119] The medicine of the present invention is made up of the following components

[0120] Lotus leaf: 3750g Salvia: 625g Hawthorn: 1875g Senna leaf: 187.5g Psoralen: 625g

[0121] Wash the above five flavors and senna leaves, soak three times with 10 times the amount of hot water at 90°C, 30 minutes each time, combine the three times of medicinal liquid, filter, and set aside the filtrate; crush Salvia miltiorrhiza into coarse powder, heat with 3 times the amount of 95% ethanol Reflux for 1.5 hours (65°C), filter, recover the ethanol from the filtrate, and obtain the ethanol extract of Danshen, and set aside; add 10 times the amount of water to decoct lotus leaves, psoralen, hawthorn and Danshen medicinal residues twice, 2 hours each time, Filtrate the decoction, combine the filtrate with the senna leaf filtrate, concentrate under reduced pressure to a relative density of 1.20 (60°C), and place it until the temperature of the liquid medicine drops to about 40°C, add 2 times...

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Abstract

The invention relates to application of a hedan preparation in preparation of a diabetes medicine. The hedan preparation adopts lotus leaves as the main medicine and adopts lotus leaves, red-rooted salvia roots, hawthorns, folium sennae and fructus psoraleae as the prescription medicines; the hedan preparation has the functions of reducing phlegm and descending the turbid and promoting blood circulation to remove blood stasis, and is clinically used for a patient with hyperlipemia phlegm stagnation symptoms. According to the research and the accidental discoveries, the hedan preparation has the effect of treating diabetes mellitus.

Description

technical field [0001] The invention relates to the application of traditional Chinese medicine prescriptions, especially the application of Hedan preparation in the preparation of diabetes drugs. technical background [0002] Diabetes mellitus (DM) is a common genetic predisposition to glucose metabolism and endocrine disorders, which in turn causes systemic metabolic disorders, accompanied by chronic progressive and persistent rise in "hyperglycemia" before treatment. The characteristic pathological and clinical changes are caused by absolute and relative insufficient insulin secretion, or the body's greatly increased demand for insulin, and the combined effects of endogenous and exogenous factors, such as thirst, polydipsia, polyphagia, and polyuria , Weight loss, fatigue, emaciation and other clinical syndromes. Although the etiology of diabetes has not been elucidated, it is currently believed that absolute or relative insulin deficiency or insulin resistance is the ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P3/10A61K127/00
Inventor 何凯南曾英姿周万辉安少凯赵磊陈武
Owner NANCHANG JISHUN PHARMA CO LTD