Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine extract and preparation method thereof

A technology of extracts and natural medicines, applied in drug combinations, pharmaceutical formulas, anti-tumor drugs, etc., can solve the problems of patients with dehydration, acid-base balance imbalance, malnutrition, etc., achieve increased inhibition, enhanced inhibition, and good side effects Effect

Inactive Publication Date: 2013-07-10
张宗升
View PDF0 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof
  • Traditional Chinese medicine extract and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of the concentrated extract of Andrographis alisma in water

[0032] Take Alisma and Andrographis paniculata according to the compatibility ratio of 1:1, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, add 6 times the amount of distilled water to the medicinal residue, and Soak, decoct, filter, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a yellow powder.

[0033] (2) Preparation of Alisalpine alcohol B acetate

[0034] Alisma coarse powder was percolated with 80% ethanol, and the ethanol was recovered to 10%, and the obtained oily extract was applied to a silica gel column, and after elution with a volume ratio of 10:1 petroleum eth...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a natural pharmaceutical composition, a preparation method thereof and application thereof in preparation of toxicity reducing and efficacy enhancing drugs for cancer chemotherapy. The natural pharmaceutical composition consists of a decoction concentrated extract of rhizoma alismatis and andrographis paniculata (Burm.f.) Nees, alisol B acetate and andrographolide which are in the ratio of (3-6):(1-6):(3-8). The composition has an excellent treatment effect on cancer-chemotherapy-related diarrhea and can simultaneously play a synergic role in cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of andrographolide, alisma terpene alcohol B acetate and andrographolide, the natural medicine composition The preparation method and the use of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea. In rec...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/884A61P1/12A61P35/00A61K31/365A61K31/58
Inventor 张宗升
Owner 张宗升
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com