Medicinal composition for treating diabetes, and its application

Abstract

The invention relates to a medicinal composition for treating diabetes, and its application in the preparation of medicines for treating the diabetes. The medicinal composition comprises glycine and metformin hydrochloride, and the best mass ratio of glycine to metformin hydrochloride is 3:1, 4:1 or 5:1. The cooperation of glycine and metformin hydrochloride realizes a reinforced effect or a synergistic effect, so the use effect of the medicinal composition can be improved. The administration concentrations of glycine and metformin hydrochloride are reduced on the premise that a same treatment effect is obtained, so the generation risk of adverse reactions is reduced.

Description

technical field

[0001] The invention belongs to the technical field of drugs for treating diabetes, and in particular relates to a pharmaceutical composition of glycine and metformin and its application as a drug. Background technique

[0002] Diabetes is a common chronic disease, mainly due to the absolute or relative lack of insulin in the blood, which leads to high blood sugar and diabetes, and then causes fat and protein metabolism disorders. Clinically, polyuria, polydipsia, polydipsia, and polyphagia may occur. Emaciation and other manifestations, severe cases are prone to acute complications such as ketoacidosis or chronic complications such as blood vessels and nerves. Metformin hydrochloride (Metformin) is a commonly used hypoglycemic drug, which has multiple mechanisms of action, including delaying the uptake of glucose from the gastrointestinal tract, increasing peripheral glucose utilization by improving insulin sensitivity, and inhibiting liver and kidney hypera...

Images