Method for preparing medical collagen sponge from East sea dark gensing

A technology of collagen sponge and sea cucumber collagen, which is applied in the field of manufacturing medical collagen sponges of Donghai black ginseng, can solve the problems of difficult removal of dirt and difficult access to Donghai black ginseng products, and achieves unbreakable, fine pores, and energy saving Effect

Active Publication Date: 2013-11-27
宁波超星海洋生物制品有限公司
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is very difficult to remove this layer of dirt. It is difficult for Donghai black ginseng products to meet the national mandatory standard GB2762-2012 "National Standard for Food Safety / Pollution in Food" by conventional cleaning and cleaning with sodium hydroxide and hydrogen peroxide. Requirements of GB2733-2005 "Hygienic Standards for Fresh and Frozen Animal Aquatic Products" and NY / T1514-2007 "Green Food Sea Cucumber and Its Products" standard of the Ministry of Agriculture
From the test results of Donghai black ginseng products collected in the market, the harmful heavy metals exceed the national standard by tens to hundreds of times, which is the fundamental reason why the rich resources of Donghai black ginseng have not been effectively utilized and industrialized

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1: the method for making medical collagen sponge with Donghai black ginseng according to the present invention, the steps are as follows:

[0027] (1) First, soak 100 kg of Donghai black cucumber that has undergone decontamination treatment (see the inventor’s authorized patent for the treatment method: A processing method for Donghai sea cucumber, ZL 2009 1 0098389.7), soak it in hot water at 95-98°C for half an hour , use a stainless steel refiner to grind into pulp, pass through a 40-mesh screen, add to a stainless steel enzymatic hydrolysis tank, add tap water twice the weight of Donghai black cucumber, add 0.1 kg of pepsin to the material, and use analytically pure L-lactic acid Adjust the pH of the material to 3.0, turn on the mixer of the enzymatic hydrolysis tank (30 revolutions per minute), turn on the jacket of the enzymatic hydrolysis tank to heat the steam, and enzymolyze at 35-36°C for 12 hours;

[0028] (2) After the enzymatic hydrolysis is comple...

Embodiment 2

[0036] Embodiment 2: the method for making medical collagen sponge with Donghai black ginseng according to the present invention, the steps are as follows:

[0037] (1) First, soak 500 kg of Donghai black cucumber that has undergone decontamination treatment (see the inventor’s authorized patent for the treatment method: A processing method of Donghai sea cucumber, ZL 2009 1 0098389.7), soak it in hot water at 95-98°C for half an hour , use a stainless steel refiner to grind into pulp, pass through a 40-mesh screen, add to a stainless steel enzymolysis tank, add tap water 1.5 times the weight of Donghai black cucumber, add 0.6 kg of pepsin to the material, and use analytically pure L-lactic acid Adjust the pH of the material to 3.0, turn on the mixer of the enzymatic hydrolysis tank (30 revolutions per minute), turn on the jacket of the enzymatic hydrolysis tank to heat the steam, and enzymolyze at 35-36°C for 18 hours;

[0038] (2) After the enzymatic hydrolysis is completed,...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a method for preparing medical collagen sponge from East sea dark gensing, which comprises the following steps: adding pepsase into East sea dark gensing defibrination going through dirt removing process; adding solid edible salt after the enzymolysis; salting, separating and collecting pulpy sediment, precipitating liquid, salting again, and separating; dissolving pulpy sediment by L- lactic acid, carrying out desalination process to the dissolved sea cucumber collagen liquid, adding food grade glutamine transaminase, spraying nepheloid sea cucumber collagen liquid into a mould, quick-freezing and forming the collagen liquid into collagen sponge instantly; freezing, alternating temperature and drying, and drying the material until the content of water is 1 to 3 %; withdrawing the collagen sponge, packing, irradiating, and entering the medical collagen sponge library. The method has the beneficial effects that East sea dark gensing is used as raw material to prepare the medical collagen sponge, the rich marine resource is enabled to be highly utilized, the sponge can also be used for crowd rejecting the mammal collagen, the problem of chemical residue in the product is solved, and the safety of the product is higher.

Description

technical field [0001] The invention belongs to the field of marine biological innovative medicine and new marine biological materials, and relates to a method for manufacturing medical collagen sponges from black ginseng of the East China Sea. Background technique [0002] Medical collagen sponge is a common surgical material with a wide range of uses. It is mainly used for hemostasis during surgery and to prevent mutual adhesion between tissues. It can be completely degraded and absorbed by tissues after surgery. It can induce the derivation and aggregation of fibroblasts, stimulate collagen production and arrangement, stimulate the formation of capillaries, ensure the blood supply and oxygen supply required for the growth of granulation tissue, regulate the functions of different cells, accelerate the absorption and secretion of collagen, and promote wound repair and healing , to prevent postoperative complications. Medical collagen sponges can also be further processed ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C12P21/06C07K1/36C07K1/30C07K1/34A61L15/32
Inventor 章元炳叶再府叶再镯叶晨
Owner 宁波超星海洋生物制品有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap