Calcium zinc gluconate granule and its preparation method

Abstract

The invention discloses calcium zinc gluconate granules and a preparation method thereof. The calcium zinc gluconate granules contain calcium gluconate, zinc gluconate, lysine hydrochloride, an excipient, a sweetening agent, an adhesive and essence. The excipient can be selected from sucrose, lactose, maltose and maltodextrin; an acidulant cannot be selected; the sweetening agent can be selected from steviosin and sucralose; the adhesive is preferably selected from the sucrose, the maltose and the maltodextrin. Compared with oral solution, the granules disclosed by the invention have more stable quality, good taste, convenience in medicament taking, and high compliance.

Description

technical field [0001] The invention relates to a calcium zinc gluconate granule and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] When children lack calcium, it is difficult to fall asleep, difficult to enter deep sleep, crying after falling asleep, easy to wake up, sweating after falling asleep; paroxysmal abdominal pain, diarrhea, cramps, "X'-shaped legs, "O"-shaped legs, chicken breasts, Gray nails or white marks; anorexia, partial eclipse; daytime irritability, restlessness; late mental development, late speech; Sparse hair; poor health, easy to catch a cold, etc. [0003] Zinc is a component or coenzyme of six major enzymes and 200 metalloenzymes in the human body, and plays a broad role in systemic metabolism. When zinc is deficient, the prominent manifestations are loss of appetite, growth retardation, pica and dermatitis, which mostly occur in children less than six years old. [0004] Lysine hydrochlori...

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