Test strip for detecting samples
A technology of test strips and samples, which is applied in the field of test strips for testing samples, which can solve problems such as differences in test results, different bonding strength of gold standard pads, loose bonding, etc., and achieve the effect of reducing broken lines and color differences
Inactive Publication Date: 2014-01-15
ABON BIOPHARM HANGZHOU
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Problems solved by technology
However, when these test strips are actually used to detect the analyte in the sample, there are some problems: because the test strips are mass-produced, each test strip needs to be cut during the production process, and after cutting, The adhesive force on the surface of the test strip is different from the pressure on both sides of the blade, so the adhesive force between the adhesive on both sides of the test strip and the sample pad, gold standard pad, etc. is different. Generally, one side of the test strip (such as the left side ) The self-adhesive is tightly bonded to the gold standard pad, while the other side (such as the right) is loosely bonded due to different forces
In this way, when the sample is detected, the flow rate of the sample on the gold-labeled pad is different due to the different thickness of the gold-labeled pad, resulting in uneven binding between the gold-labeled antibody and the analyte in the sample, which will eventually lead to the display of the test result—detection Lines or control lines are broken, that is, the lines are not displayed completely
At the same time, there are also differences in the test results when the same sample is tested with the same batch of test strips
Thus, it seriously affects the reading and judgment of the test results
Method used
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Abstract
The invention relates to a device for detecting samples and in particular relates to a test strip for detecting samples. The test strip for detecting samples comprises a gold-labeled pad and a detection pad, and also comprises a gold-labeled buffer pad. Because the gold-labeled buffer pad exists in the test strip, the sample is fully reacted with an antibody. Meanwhile, an outer adhesive sticker is separated from the inner gold-labeled pad, so that a phenomenon that heights of two sides of the gold-labeled pad are different is avoided or the difference between heights of two sides of the gold-labeled pad is reduced in a test strip production process, and the speeds of the samples flowing through the gold-labeled pad are the same. Therefore, analytes in the samples can be fully combined with antibodies with gold labels. Finally, the phenomena of breakage of a test structure line and color difference are effectively reduced.
Description
technical field [0001] The invention relates to a device for detecting samples, especially a test strip for detecting samples. Background technique [0002] The technique of using the principle of immunological binding reaction to detect the presence or absence of analyte in a sample is widely used in various fields. It can be used to detect analytes in various biological samples (saliva, blood, urine, serum, sweat, etc.) to monitor diseases and human health conditions (early pregnancy, tumors, infectious diseases, drugs, etc.). The fundamental principle of this detection technology is based on the specific binding properties between immune molecules, such as antibody and antigen, hapten / antibody, biotin and anti-biotin, etc. In addition, many of these assays can be performed on solid media, such as commonly used lateral flow reagent strips, glass or plastic multiwell plates, immunochromatographic devices, and the like. Usually, some solid particles or chemical substances...
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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/558
CPCG01N33/558
Inventor 赵福铨伍欣
Owner ABON BIOPHARM HANGZHOU
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