A circulating tumor cell capture instrument and its capture staining method

A tumor cell and capture instrument technology, applied in the field of circulating tumor cell capture instrument and capture and dyeing, can solve the problems of affecting experimental results, operation errors, and single implementation throughput, so as to shorten the operation time, increase the throughput, and improve the accuracy. Effect
CN103604679BActive Publication Date: 2015-12-30WUHAN YZY MEDICAL SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
WUHAN YZY MEDICAL SCI & TECH
Publication Date
2015-12-30

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Abstract

The invention discloses a capture instrument for circulating tumor cells. The capture instrument comprises a multi-way valve device, a wheel disc device, a sample loading needle device and an injector device, wherein the multi-way valve device is connected with a reagent bag, different kinds of reagents can be selected through the multi-way valve device, the wheel disc device is provided with a filter, the sample loading needle device can be inserted into the filter of the wheel disc device so as to be communicated with an air path and a liquid path, the injector device absorbs the required reagent through the multi-way valve device and then injects the reagent into the filter. Furthermore, the invention also discloses a method for capturing and staining by using the capture instrument for circulating tumor cells. The retention rate of the capture instrument in capturing tumor cells is higher than that of manual capturing; furthermore, compared with manual staining, the capture instrument for circulating tumor cells has high degree of uniformity and consistency in staining, and is clean in background.
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Description

technical field

[0001] The invention relates to a biological detection instrument, in particular to a circulating tumor cell capture instrument and a capture staining method. Background technique

[0002] Tumor micrometastases originate from invading circulating tumor cells. Therefore, circulating tumor cells (circulating tumor cells, CTCs) may be a sign of distant metastasis of tumors. In recent years, with the development of sensitive molecular techniques, it has become possible to separate and count peripheral blood CTCs. In the early stage of the disease, CTCs may help to differentiate benign and malignant tumors, and predict and judge the risk of metastasis; in the advanced stage of the disease, CTCs may provide important prognostic information and help doctors monitor the effect of treatment; and CTCs may reflect tumor The characteristics can guide the formulation of treatment plan and can be used as the target of targeted therapy. There are many methods for the sepa...

Claims

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