Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Schiff base fluorescent polymer and preparation method thereof

A fluorescent polymer and Schiff base technology, applied in the field of fluorescent probe detection, can solve the problems of further improvement of photostability, and achieve the effects of strong binding recognition performance, excellent performance, and high fluorescence quantum yield

Inactive Publication Date: 2014-05-07
QILU UNIV OF TECH
View PDF5 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Fluorescence method has many advantages such as convenience, speed, and high sensitivity in the detection of metal ions and DNA. However, organic small molecule fluorescent probes are mostly used in fluorescence methods. Sensitivity needs to be further improved

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Schiff base fluorescent polymer and preparation method thereof
  • Schiff base fluorescent polymer and preparation method thereof
  • Schiff base fluorescent polymer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The Schiff base fluorescent polymer has the molecular structural formula as the aforementioned formula I. The preparation method steps are as follows:

[0044] a. Synthesis of 4-aminopolystyrene: put 1g of 4-nitropolystyrene in a flask, stir at a high speed at 75°C, add 16g of sodium hydroxide and 5g of sodium dithionite, react for 4 hours, and filter the resulting mixture , washing and drying to obtain 4-aminopolystyrene. ( 1 H NMR: (DMSO, 400MHz, TMS) δ (ppm): 7.80 (s, 2H, -NH 2 );6.99(m,4H);1.5(m,3H).IR(KBr)ν / cm -1 :3420cm -1 (-NH 2 );2925,2855cm -1 (-CH 2 );1612,1515,1453cm -1 (Ar–C=C);849cm -1 (Ar-C-H);

[0045] b. Preparation of small molecule fluorescent compound II: Add 3.0g of 4,4'-diformyltriphenylamine, 3.0g of 1,10-phenanthroline-5,6dione and 215mL of glacial acetic acid into a three-necked flask, and magnetically stir Slowly raise the temperature to 115°C, and add 8.5g of ammonium acetate in batches, reflux for 3h, cool to room temperature, then ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a Schiff base fluorescent polymer with a structure shown in a formula I and a preparation method thereof. The preparation method comprises the following steps: reducing 4-nitro polystyrene into 4-amino polystyrene, reacting 4,4-biformyl triphenylamine with 1,10-phenanthroline-5,6-diketone to synthesize a small molecule fluorescent compound II, and finally, carrying out a Schiff base reaction between the small molecule fluorescent compound II and the 4-amino polystyrene, cooling, washing and drying to prepare the Schiff base fluorescent polymer. The Schiff base fluorescent polymer can have high identification performance to DNA and metal ions and can be used as a polymer type fluorescence probe. (img file='DDA0000454216050000011.TIF' wi='1128' he='952' / ).

Description

technical field [0001] The invention relates to a Schiff base fluorescent polymer and a preparation method thereof, belonging to the technical field of fluorescent probe detection. Background technique [0002] DNA is a very important genetic material of life. The detection and analysis of its content and its location identification have important applications in genomics, virology, molecular biology, cytology, etc. Therefore, it is of great significance to identify and detect DNA. Currently, commonly used methods for detecting DNA include chromatography, spectrophotometry, microphotometry, and immunoassay. [0003] The detection of metal ions is of great significance in the human body and the environment. Through the detection of metal ions, the relevant enzyme catalysis of the human body, the mechanism of hormone action and the metabolic process of the human body can be studied, and then the disease can be effectively found, so as to carry out timely treatment. For the ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C09K11/06C07D471/16C08F112/14C08F8/30G01N21/64
Inventor 张献秦元安张静静
Owner QILU UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com