1results about How to "Good amphipathy" patented technology

This invention discloses a soybean phospholipid-based nanoemulsion and its preparation method, belonging to the fields of molecular biology and biomedicine. This invention addresses the technical problem of refining the particle size and improving the stability of existing soybean phospholipid-based nanoemulsions for use in fine pharmaceuticals. A method for preparing a soybean phospholipid-based nanoemulsion includes the following steps: S1, modified glycerol phosphorylcholine and cholesterol are mixed in ethanol, then phosphatidylethanolamine and a composite stabilizer are added to form an oil phase; deionized water, glycerol, and polyether F68 are mixed to form an aqueous phase; S2, the oil phase is injected into the aqueous phase and homogenized at high speed to obtain a preliminary mixture; the pH of the preliminary mixture is adjusted to prepare a primary emulsion; the primary emulsion undergoes low-pressure homogenization followed by high-pressure homogenization to obtain a nanoemulsion; the nanoemulsion is filtered through a microporous membrane to obtain the soybean phospholipid-based nanoemulsion. The nanoemulsion prepared by this invention has the advantages of small particle size and good photothermal stability.