Medicine for treating diabetic foot disease and preparing method thereof

A technology for diabetic foot disease and medicine, which is applied in the field of medicine to achieve the effects of anti-fungal infection microcirculation, improving microcirculation and promoting skin metabolism

Active Publication Date: 2014-05-14
杨洪英 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And do not see the literature report and the application of the medicine identical with the present invention for the treatment of diabetes

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The raw material weight ratio of the medicine for the treatment of diabetic foot disease of the present invention is as follows:

[0022] Rattan Panax notoginseng 30g Osteospermum 15g Angelica 6g

[0023] Chuanxiong 3g Radix Paeoniae Rubra 6g Blood Dried 1g

[0024] Da Xueteng 9g Achyranthes knuckle 5g Rhubarb 3g

[0025] Phellodendron 7g, Baizhi 6g, Angelica dahurica 1g

[0026] Borneol 3g Ketoconazole 0.5g

[0027] Preparation:

[0028] 1) Soak 12 medicines except borneol and ketoconazole for 24 hours, extract them with water for 3 times: 1.5 hours for the first time; ;

[0029] 2) Finely powder the borneol into a fine powder of 120 mesh;

[0030] 3) Mix dry paste powder with fine powder of borneol;

[0031] 4) The mixed powder is made by heating and fusing 670g of olive oil and 330g of beeswax, with a melting point of 62°C;

[0032] 5) Dissolve ketoconazole at 80°C, add the fusion compound in step 4), stir and mix evenly, then pack into ointment.

Embodiment 2

[0034] The medicine raw material weight ratio for the treatment of diabetic foot disease of the present invention is as follows:

[0035] Rattan Panax notoginseng 60g Osteophytum 30g Angelica 12g

[0036] Chuanxiong 10g, Radix Paeoniae Rubra 12g, Dried Blood 3g

[0037] Daxueteng 15g, Achyranthes knuckle 12g, rhubarb 12g

[0038] Phellodendron 15g, Baizhi 15g, Angelica dahurica 5g

[0039] Gallnut 10g, borneol 5g, ketoconazole 0.5g

[0040] Preparation:

[0041] 1) Soak 12 medicines except borneol and ketoconazole for 24 hours, extract them with water for 3 times: 1.5 hours for the first time; ;

[0042] 2) Finely powder the borneol into a fine powder of 120 mesh;

[0043] 3) Mix dry paste powder with fine powder of borneol;

[0044] 4) The mixed powder is made by heating and fusing 680g of olive oil and 340g of beeswax, with a melting point of 67°C.

[0045] 5. Dissolve ketoconazole at 75°C, add the fusion compound in step 4), stir and mix evenly, then pack into ointm...

Embodiment 3

[0047] The medicine raw material weight ratio for the treatment of diabetic foot disease of the present invention is as follows:

[0048] Rattan notoginseng 45g Osteospermum 20g Angelica 8g

[0049] Chuanxiong 7g Radix Paeoniae Rubra 8g Blood Dried 2g

[0050] Da Xueteng 12g, Achyranthes knuckle 9g, rhubarb 8g

[0051] Phellodendron 11g, Baizhi 12g, Angelica dahurica 3g

[0052] Borneol 4g Ketoconazole 0.5g

[0053] Preparation method is identical with embodiment 1 or embodiment 2.

[0054] Following is the clinical trial situation of the present invention:

[0055] 1. Information

[0056] 1. General information

[0057] 229 cases were outpatients of Kunming Friendship Hospital and Baoyuantang Diagnostic Clinic. From January 2009 to January 2011, they were divided into two groups by random number table method. There were 119 cases in the treatment group, 72 males and 47 females. Aged 25-76 years old, average (43.62±8.23) years, course of disease 9-32.1 years, average (1...

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PUM

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Abstract

The invention relates to a medicine for treating the diabetic foot disease and a preparing method thereof. The medicine comprises, by weight, 30-60 of anredera cordifolia, 15-30 of garden balsam stems, 6-12 of angelica sinensis, 3-10 of liguticum wallichii, 6-12 of roots of common peony, 1-3 of dragon's blood, 9-15 of sargentgloryvine stems, 5-12 of the root of bidentate achyranthes, 3-12 of rheum officinale, 7-15 of golden cypress, 6-15 of rhizome bletillae, 1-5 of radix agelicae, 3-5 of borneol, and 0.5-1 of ketoconazole. The medicine has the effects of clearing heat and toxic materials, promoting blood circulation to remove blood stasis, removing thee necrotic tissue and promoting granulation, stopping bleeding by astringency, and stopping pain, is antimicrobial, anti-infection, anti-inflammatory, antibiosis, antioxidant, anti-aging, anticancer, antifungal, and fungal injection preventing, improves microcirculation, and promotes skin metabolism. The medicine mainly treats the diabetic foot disease, deep-rooted boil, ulcers and sores, swelling of ulcerated muscle, skin crowfoot cracks, furuncle boils, and the like.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicine for treating diabetic foot disease and a preparation method thereof. Background technique [0002] According to the current global survey, by 2025, there will be more than 250 million people with diabetes, and diabetic foot disease will cost the most, because 85% of diabetic distal amputations are caused by foot ulcers, the most important cause of foot ulcers. Factors are peripheral neuropathy, foot trauma, foot deformity, and loss of sensation in the foot, leading to amputation. Different regions, different economies, and different unfavorable factors cause foot ulcers to prolong, which can lead to foot infection, gangrene, and amputation. [0003] Diabetic foot disease is a foot deformity caused by diabetic peripheral nerve (including sensory nerve, autonomic and motor nerve) lesions and (or) peripheral small artery occlusion caused by atherosclerosis of the low...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/06A61P17/02A61P3/10A61K31/045A61K31/496
Inventor 杨洪英段复华
Owner 杨洪英
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