Black cumin seed oil nose drop and preparation method thereof

A technology of black cumin seeds and oil nasal drops, which is applied in anti-inflammatory agents, medical formulas, non-central analgesics, etc., can solve the problems that there is no black cumin seed, and achieve the effect of expanding the scope of medical use

Active Publication Date: 2014-06-04
徐凌川 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Apart from this, there are currently no other formulations of Nigella

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Take 100 g of Semen Nigella coarse powder, add 10 times the amount of petroleum ether, ultrasonically extract twice, each time for 1 hour, combine the two filtrates, recover the solvent under reduced pressure, and obtain oil for later use;

[0064] Mix 30 g of Nigella seed oil with 5 mL of polysorbate-80 and add it to the aqueous solution; dissolve 1.5 g of CMC-Na in 50 mL of distilled water, add the above liquid after heating and swelling; add 4.5 g of NaCl, and add 3% borax Adjust the pH of the solution to 6-7, dilute to 500 mL with distilled water, stir well, refrigerate for 48 h, put nasal drops into plastic bottles, and sterilize with cobalt 60 to get the solution.

Embodiment 2

[0066] The medicinal materials were weighed in proportion: 30g of Nigella seed oil, 25g of ephedra, 25g of ramie, 20g of magnolia, 20g of Angelica dahurica, 35g of Goose Bubivora, 25g of Schizonepeta, and 25g of Fangfeng.

[0067] Extraction of volatile oil: take the coarse powder of chrysanthemum, magnolia, nepeta, and angelica dahurica, add medicinal materials according to the above ratio, soak in 10 times the amount of water for 2 h, and reflux for 6 h. Store the obtained volatile oil for future use; filter the distilled aqueous solution, and use the dregs and filtrate for future use respectively;

[0068] Extraction of water decoction: take ephedra, goose herbivore, and parsnip and add 12 times the amount of water to soak for 2 hours, then combine with herbaceous ramie, magnolia, schizonepeta, and angelica dahurica, and decoct to extract. Decoct for 30 minutes for the first time, filter out; add 8 times the amount of water for the second time, decoct for 30 minutes, filter...

Embodiment 3

[0073] Take 25g of nigella seed oil, 20g of ephedra, 20g of ramie, 15g of magnolia, 15g of angelica dahurica, 30g of geese not eating grass, 20g of nepeta, and 20g of wind;

[0074] Extraction of volatile oil: take the coarse powder of chrysanthemum, magnolia, nepeta, and angelica dahurica, add medicinal materials according to the above ratio, soak in 10 times the amount of water for 2 h, and reflux for 6 h. Store the obtained volatile oil for future use; filter the distilled aqueous solution, and use the dregs and filtrate for future use respectively;

[0075] Extraction of water decoction: take ephedra, goose herbivore, and parsnip and add 12 times the amount of water to soak for 2 hours, then combine with herbaceous ramie, magnolia, schizonepeta, and angelica dahurica, and decoct to extract. Decoct for 30 minutes for the first time, filter out; add 8 times the amount of water for the second time, decoct for 30 minutes, filter out, combine the decoction with the filtrate...

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PUM

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Abstract

The invention relates to black cumin seed oil nose drop and a preparation method thereof. The black cumin seed oil nose drop is prepared from black cumin seed oil or from black cumin seed oil, scabrous mosla herb, herba ephedra, radix angelicae, violet magnolia, centipeda minima, schizonepeta and radices sileris in a compounding manner. The black cumin seed oil nose drop disclosed by the invention is used for directly acting on the mucosa of the nasal cavity, becomes effective rapidly, and can relieve inflammatory cell infiltration of the nasal mucosa caused by rhinitis and nasosinusitis and inhibit hyperplasia of connective tissues below the mucosa so as to improve nasal obstruction caused by swelling of the nasal mucosa, so the black cumin seed oil nose drop is suitable for treating various rhinitis and has a better effect than clinical commonly-used biyanling pills, centipeda minima nasal drops and the like.

Description

technical field [0001] The invention relates to a black cumin seed oil nasal drop for treating rhinitis and a preparation method thereof, and belongs to the technical field of nasal drop preparation prepared from Uighur medicine extract and pharmaceutical auxiliary materials. technical background [0002] Rhinitis belongs to the category of rhinitis in traditional Chinese medicine. Its etiology and pathogenesis are mostly formed by feeling the evil of wind-heat or wind-cold entering the interior to transform heat, and blocking the nasal orifice with toxic heat and turbid tears. Chronic patients are mostly due to weak spleen and lungs, insufficient lung qi to the point of weak defense, and are susceptible to exogenous pathogens. Insufficiency of the spleen leads to failure of transportation and transformation, retention of phlegm dampness, trapped nose orifices, soaking in the sinus mucosa to form sinusitis. Traditional Chinese medicine has reliable curative effect in treat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P11/02A61P29/00
Inventor 田易玲徐凌川王辉
Owner 徐凌川
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