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Nuisance-free antibiotic insecticidal preparation for aquatic product culturing, and preparation method thereof

An aquaculture and preparation technology, applied in the directions of insecticides, nematicides, botanical equipment and methods, etc., can solve the problems of unsatisfactory actual effect, secondary pollution of water bodies, large side effects, etc. The effect of protecting the ecological environment and prolonging the shelf life

Inactive Publication Date: 2014-08-20
ZHUHAI KANGYIDA BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Azadirachtin has various effects on insects, such as refusal, avoidance, growth regulation and sterilization. It has achieved good results as an insecticide in agriculture, but azadirachtin is used as a drug for preventing and controlling fish parasitic diseases There are very few researches on the application of this field in the world, and the existing technologies have copied the application method of azadirachtin in other agricultural fields such as planting, such as the published Chinese patent application "aquatic animal insecticide" (publication number CN102429896A) , is to compound azadirachtin extract, cypermethrin benzene oil, high chlorine emulsifier, dimethylamide, and xylene into an emulsion, and use the whole pool to prevent and control aquatic parasites. The actual effect is not ideal. In fact, Or chemical drugs are at work, and it is very easy to cause secondary pollution to the water body
In particular, pyrethroids are toxic to crustacean aquatic animals such as shrimp, and the side effects are too great

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Production concentration is 18% azadirachtin and lysozyme mixed water dispersible granules, the proportioning of each component is:

[0028] (1) Add 10% (weight) azadirachtin dry powder;

[0029] (2) Add 8% (weight) lysozyme dry powder

[0030] (3) add 2% (weight) of pulling powder

[0031] (4) Add 5% (weight) of NNO

[0032] (5) Add 3.5% (weight) of ammonium sulfate

[0033] (6) Add 2.5% (weight) of 020lB

[0034] (7) Add 0.1 (weight) of polyvinyl alcohol

[0035] (8) Add 68.9 (weight) of white carbon black that pre-adjusts the pH value to 5.5

[0036] The formula mixture is ultrafinely pulverized, then granulated, dried and sieved to obtain the product.

Embodiment 2

[0038] Production concentration is 3% azadirachtin and lysozyme mixed water dispersion, the ratio of each component is:

[0039] (1) add 1.8% (weight) of azadirachtin dry powder

[0040] (2) add 1.2% (weight) lysozyme dry powder

[0041] (3) Add 10% (weight) Tween as wetting agent

[0042] (4) add 10% (weight) methyl cellulose as binder

[0043](5) Add 15% (weight) dry starch as disintegrant

[0044] (6) adding 55% (weight) kaolin pre-adjusted to a pH value of 5.5 as filler

[0045] The formula material mixture is ultrafinely pulverized, then granulated, dried and sieved to obtain the product.

Embodiment 3

[0047] Production concentration is 58% azadirachtin and lysozyme mixed water dispersible granules, the proportion of each component is:

[0048] (1) add 40% (weight) azadirachtin dry powder

[0049] (2) add 18% (weight) lysozyme dry powder

[0050] (3) Add 11% (weight) sucrose ester as wetting agent

[0051] (4) Add 13% (weight) starch as binder

[0052] (5) Adding 8% (weight) sodium methyl starch is a disintegrant

[0053] (6) add 17% (weight) the bentonite that pre-adjusts pH value to 5.5 as filler

[0054] The formula material mixture is ultrafinely pulverized, then granulated, dried and sieved to obtain the product.

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Abstract

The invention relates to a parasite and bacterial disease control preparation applied in the field of aquatic product culturing, and a preparation method thereof. The preparation is a granule which can be rapidly dissolved in water, and contains 1-45% of dry nimbin powder, 1-25% of dry lysozyme powder, 1-10% of a wetting agent, 1-8% of a dispersant, 1-5% of a disintegrating agent, 1-10% of an emulsifier, 0.01-2% of a binder, and a proper amount of a filler. The preparation is water dispersible granule, utilizes the synergistic effect of nimbin and lysozyme, realizes the synchronization of desinsection, antibiosis and antiphlogosis, and has an obvious treatment effect. The pH value of the preparation is 4-6, guarantees the stability of active substances and realizes a long shelf life. The preparation compounding natural insecticidal and antibiotic substances overcomes the drug resistance, and has the advantages of wide spectrum, high efficiency, low toxicity, no pollution and no residual, so the preparation can substitute traditional chemical pesticides and antibiotics, creates favorable conditions for nuisance-free aquatic product culturing modes, and protects the ecologic environment and the food safety of consumers.

Description

technical field [0001] The invention relates to a preparation method of a pharmaceutical preparation for preventing and controlling parasitic bacterial diseases used in pollution-free aquaculture, in particular to a method for synchronously killing parasites in aquatic animals by compounding azadirachtin and lysozyme and antibacterial and anti-inflammatory , a preparation method of a double-effect innovative preparation and its application in the field of aquaculture. Background technique [0002] Fish parasitic disease is one of the main diseases in the fish farming industry. Its epidemic area is wide and the time is long, which can cause a large number of fish deaths. In the past, the use of pesticides and heavy metal salts in aquaculture to control fish parasitic diseases was effective, but with the passage of time, drug resistance continued to emerge. At the same time, these drugs have cumulative residual effects on aquatic organisms, which can cause quality problems in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61P33/00A61P31/04A61P17/00A61P1/00A01N63/02A01P1/00A01P17/00A01P5/00A01P7/04A01N43/90A61K36/58A61K31/352
Inventor 徐文中董燕声
Owner ZHUHAI KANGYIDA BIOTECH
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