A fully automatic pipetting device

Abstract

The invention provides a full-automatic liquid transfer device. The device comprises a mounting plate, an active plate, pipettes, piston rods and a driving component, wherein the active plate is connected on the mounting plate and can move along the height direction of the mounting plate; the pipettes are detachably fixed on the mounting plate; the piston rods are fixed on the active plate; the driving component is used for driving the active plate to move relative to the mounting plate; an insertion hole is formed at the upper end of each pipette, and an opening is formed at the lower end of each pipette; the lower ends of the piston rods are inserted in the pipettes via the insertion holes of the pipettes; a piston hermetically fit with the inner wall of each pipette is arranged at the lower end of each piston rod; the driving component comprises a driving motor, a transmission screw and a screw nut; a body of the driving motor is partially fixed on the mounting plate; the transmission screw extends along the height direction of the mounting plate and is synchronously connected with a rotating shaft of the driving motor; the screw nut is in thread-fit with the transmission screw and is fixed on the active plate. The device has a simple structure, reduces the equipment cost and simultaneously ensures the accuracy of the dosages of added reagents.

Description

technical field [0001] The invention relates to the technical field of biomedicine, and specifically relates to a fully automatic pipetting device. Background technique [0002] In the biologically active substance extraction devices used in the fields of disease control, food safety, forensic identification, and genomics, pipetting devices are usually used to transfer liquid reagents. Most of the current pipetting devices use metering pumps (or peristaltic pumps, diaphragm pumps) to pump liquids to achieve liquid transfer. Specifically, a mounting plate that moves up and down is set on the frame of the biological active substance extraction device. A row of pipettes is arranged on the mounting plate. The lower end of the pipette is open and the upper end is connected with the metering pump by a hose. , the mounting plate moves to the top of the pipette head, and the drive assembly drives the pipette to move downward and insert it into the opening of the pipette, so that th...

AI Technical Summary

Problems solved by technology

Most of the current pipetting devices use metering pumps (or peristaltic pumps, diaphragm pumps) to pump liquids to achieve liquid transfer. Specifically, a mounting plate that moves up and down is set on the frame of the biological active substance extraction device. A row of pipettes is arranged on the mounting plate. The lower end of the pipette is open and the upper end is connected with the metering pump by a hose. , the mounting plate moves to the top of the pipette head, and the drive assembly drives the pipette to move downward and insert it into the opening of the pipette, so that the pipette and the pipette are fixed and communicated. When the liquid is sucked, the metering pump works and the The reagent in the test tube is sucked into the pipette or the reagent in the pipette is pumped into the test tube. Although the pipetting device with this structure can meet the basic needs of liquid transfer, it needs to be equipped with a metering device for each pipette. The whole structure of the pump is relatively complicated, and the metering pump and the pipette are connected by a hose, which is not conducive to the miniaturization design of the extraction device; in addition, it is difficult to accurately control the dosage of the reagent when the metering pump is used, which affects At the same time, it is difficult to ensure a complete seal at the connection between the pipette and the liquid-dispensing tip. If there is air leakage at the connection between the two, it will further affect the dosage of the reagent drawn by the metering pump.

What's more inconvenient is that this method can only touch clean reagents and cannot contact with samples, otherwise it will cause serious cross-contamination

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