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Insulin pump

An insulin pump and insulin technology, applied in flow monitors, drug devices, computer-aided drug prescription/delivery, etc., can solve problems such as high variability and unoptimized accuracy

Inactive Publication Date: 2014-09-17
GENE ONYX
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The variability of these delays can be high, and the accuracy of current s.c glucose sensors is far from optimized, with absolute mean differences of up to 20%, especially in hypoglycemia, a dangerous state that needs to be avoided

Method used

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Embodiment Construction

[0039]In order to at least partially overcome the problems described above, a biologically inspired model incorporating pancreatic insulin secretion is proposed herein to optimize the control of the insulin pump for each user or patient. In particular, the present invention provides a glucose controller unit based on a computational model of beta cells of the pancreas.

[0040] Figure 2a An example of a control device 100 comprising a controller unit 102 for controlling the output of an insulin pump 112 is shown. Controller unit 102 includes user input 104 , measurement input 106 and processing logic 108 . The controller unit 102 generates a control signal 110, which is input to the insulin pump 112, which controls the level of insulin supplied by the insulin pump 112 to the patient or user. The user input 104 receives one or more gain factors or other data provided by the controller unit 102 for the user.

[0041] Figure 2b An example of an insulin pump 120 is shown com...

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Abstract

The present invention relates to a controller unit and methods for controlling an insulin pump. The controller unit includes a user input that receives a gain factor. The gain factor has been calculated based on historical data in relation to a patient. The controller unit includes a measurement input for receiving data representative of a measured blood glucose level for the patient. Processing logic of the controller unit is configured to apply the measured blood glucose level to a pancreatic beta-cell insulin secretion computational model to predict an insulin output level, apply the gain factor to the predicted insulin output level to determine a patient insulin deficiency level, and calculate a control signal for controlling the insulin output level of the insulin pump based on the patient insulin deficiency level.; Methods are provided for optimising the gain factor based on the historical data in relation to the patient.

Description

technical field [0001] The present invention relates to methods and devices for controlling an insulin pump. In particular, the invention relates to methods and devices for controlling and optimizing the performance of an insulin pump for each user. Background technique [0002] Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease characterized by indirect autoimmune destruction of T cells in the insulin-secreting β cells of the endocrine pancreas. Absolute insulin deficiency can occur, resulting in hyperglycemia. The modality used in current clinical practice for the treatment of type 1 diabetes is mainly based on subcutaneous insulin injections given several times a day or continuously in doses determined by intermittent measurements of blood glucose levels. Blood glucose level (or blood glucose concentration) includes or represents the amount of glucose in the blood of an animal or human, and is measured in molar concentration (mmol / L) according to Internation...

Claims

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Application Information

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IPC IPC(8): G06F19/00A61M5/00
CPCA61M5/142A61M2230/201A61M2005/1726A61M2005/14208A61M5/1723A61M2205/52G06F19/3468G16H20/17G16H20/60
Inventor 克里斯特弗·图马佐潘泰利斯·乔治乌波·埃雷罗·维纳卡尔文·西姆
Owner GENE ONYX
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