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Traditional Chinese medicine for treating acute purulent osteomyelitis and preparation method of traditional Chinese medicine

A technology of suppurative osteomyelitis and traditional Chinese medicine, applied in the field of pharmacy, can solve the problems of long course of treatment for acute suppurative osteomyelitis, easy generation of drug resistance, unsatisfactory curative effect, etc., and achieves low cost, low recurrence, and treatment course. short effect

Inactive Publication Date: 2014-10-01
卢士海
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] However, Western medicine has a long course of treatment for acute suppurative osteomyelitis, the curative effect is not satisfactory, drug resistance is easy to develop, and even the disease is delayed.

Method used

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Experimental program
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Effect test

preparation example Construction

[0077] Wherein, when the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0078] In the first step, mix kudzu root, ebony, trichosanthemi, astragalus, hanshuishi, anemarrhena, commelina, gardenia, scutellaria baicalensis and Burnet according to the stated ratio, add 4 to 6 times the amount of water to extract the volatile oil, and The obtained volatile oil is clathrated with β-cyclodextrin, the mass ratio of volatile oil to β-cyclodextrin is 1:3-6, stirred for 60 minutes to 90 minutes, and the temperature is 30°C-50°C to obtain the volatile oil inclusion compound, which is ready for use ; In addition, the water extract is concentrated to a clear paste with a relative density of 1.15 to 1.17 at 60°C;

[0079] In the second step, mix the rag grass, Polygonum cuspidatum, Jiyateng, Ishishanglian, Yahuazi, Coptis chinensis, Gentiana, Maweilian, Chonglou, Daxueteng, Jinguolan and Bianbacao in the stated proportion, and add...

Embodiment 1

[0097] Embodiment 1 Capsules of the present invention

[0098] Pueraria 26g, Ume 25g, Trichosanthemi 25g, Astragalus 24g, Hanshuishi 12g, Anemarrhena 16g, Commelina 30g, Gardenia 24g, Scutellaria baicalensis 28g, Burnet 29g, Ragweed 15g, Polygonum cuspidatum 29g, Chicken vine 19g, Ishigami lotus 18g, Yahuazi 24g, Coptidis 20g, Gentian 19g, Horsetail Lian 30g, Chonglou 6g, Daxueteng 22g, Golden Fruit Lam 19g, Verbaca 17g, Scrophulariaceae 22g, Purple Pearl 28g, Ramie root 22g, Panax notoginseng 24g, Agrimony 21g, Curcuma 21g and Liquidambar balm 29g.

[0099] Its preparation method comprises the following steps:

[0100] In the first step, mix kudzu root, ebony, trichosanthemi, astragalus, cold water stone, anemarrhena, commelina, gardenia, scutellaria baicalensis and Burnet according to the stated ratio, add 5 times of water to the mixture to extract the volatile oil, and obtain the The volatile oil is clathrated with β-cyclodextrin, the mass ratio of volatile oil to β-cyclo...

Embodiment 2

[0106] Embodiment 2 lozenge of the present invention

[0107] Pueraria 32g, Ume 19g, Trichosanthemi 26g, Astragalus 19g, Hanshuishi 15g, Anemarrhena 20g, Commelina 28g, Gardenia 26g, Scutellaria baicalensis 30g, Burnet 24g, Ragweed 17g, Polygonum cuspidatum 32g, Chicken vine 13g, Ishigami lotus 21g, Yahuazi 28g, Coptidis 17g, Gentiana 21g, Horsetail Lian 35g, Chonglou 7g, Daxueteng 25g, Golden Fruit Lam 25g, Herba Grass 12g, Scrophulariaceae 25g, Purple Pearl 30g, Ramie Root 18g, Panax notoginseng 27g, Agrimony 23g, Curcuma 13g and Liquidambar balm 30g.

[0108] Its preparation method comprises the following steps:

[0109] In the first step, kudzu root, ebony, trichosanthemi, astragalus, hanshuishi, anemarrhena, commelina and gardenia are mixed according to the stated ratio, and dissolved in ethanol with an alcohol concentration of 95% that is 4 times the mass of the obtained mixture, Extract after heating and reflux for 3 hours, and filter; dissolve the filter residue agai...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating acute purulent osteomyelitis and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises the following traditional Chinese medicine raw materials: kudzuvine root, dark plum, radices trichosanthis, membranous milkvetch root, gypsum rubrum, rhizoma anemarrhenae, dayflower, cape jasmine fruit, baical skullcap root, garden burnet, Stachys kouyangensis, giant knotweed, Chinese fever vine, Begonia bretschneideriana Hemsl, Pittosporum sahnianum Gowda, coptis, gentian, Thalictrum petaloideum, RhizomaParidis, Sargentodoxa cuneata, radix tinosporae, potentilla discolor, figwort, Callicarpa bodinieri Levl, Carpesium abrotanoides, panax notoginseng, Agrimonia pilosa Ledeb, turmeric and Liquidambar formosana Hance. The invention has the benefits that the traditional Chinese medicine has the effects of clearing heat-toxin, replenishing and cooling blood, and relieving pain, has a short course of treatment without recurrence after cure, can improve immunity of the human body, is convenient in manufacturing technology, low in toxic or side effects, is easy to manufacture, and is low in cost.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating acute suppurative osteomyelitis and a preparation method thereof. [0002] Background technique [0003] In acute suppurative osteomyelitis, sometimes a small number of bacteria invade the blood of normal people, but they are eliminated due to the body's resistance. For example, when the body's resistance is lowered and there is an infected lesion, the bacteria can enter the blood from the lesion, and the body fails to treat it. All of them are eliminated, and the bacteria can invade the bone along with the circulation. Whether an infection occurs depends on the body's sensitivity to infection at that time, local resistance and other conditions. [0004] The occurrence of osteomyelitis must meet two conditions, that is, the coexistence of external factors and internal factors. The invasion of the human body by highly infectious bact...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P31/04A61P19/08A61K33/06
Inventor 卢士海
Owner 卢士海
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