Traditional Chinese medicine for curing liver-kidney asthenia femoral head necrosis and preparation method thereof

A technology for necrosis of the femoral head and deficiency of the liver and kidney. It is used in pharmaceutical formulations, medical preparations containing active ingredients, and bone diseases. It can solve the problems of pain, high cost, and loose artificial femoral heads, and achieve exact curative effects. , the effect of small side effects

Inactive Publication Date: 2015-01-28
韦标方
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to improper artificial femoral head materials and human body’s own rejection, many patients have artificial femoral head loosening after surgery, requiring repeated operations, resulting in greater pain for patients, poor long-term efficacy, strict surgical indications, and many other factors and costs. Expensive, surgical treatment is not easily accepted by patients

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0042] The present invention also provides a preparation method of the above-mentioned Chinese medicine, wherein the dosage form of the Chinese medicine is granule, and the preparation method comprises the following steps:

[0043] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% that is 3 to 5 times that of the mixture, heat to boiling and reflux for 1 to 3 hours, filter, and use the percolation method Slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.03-0.05Mpa to a paste with a relative density of 1.00-1.02 at 60-70°C, spray dry, spray The air inlet temperature of the dryer is 170-180°C, and the outlet air temperature is 80-90°C, and then crushed into powder to make dry paste powder;

[0044] Step 2: Add 0.3-0.6 times of sucrose powder and 0.2-0.4 times of dextrin to the obtained dry paste powder to form granule...

Embodiment 1

[0049] Embodiment 1 Granules

[0050] Take 160g of horizontal sutra mat, 240g of Zoumatai, 60g of chrysanthemum, 70g of black sesame, 220g of lotus, 230g of mussel, 440g of ginseng, 130g of shayuanzi, 190g of shanxiangguo, 120g of nanzhuzi, 410g of Euonymus euphonium , 80g of stone brush handle, 140g of Xuemancao, 70g of Luniancao, 60g of Laolaiqing, 180g of Dayeqianjin root, 160g of thorny fruit vine and 130g of Heipi Dieda;

[0051] Prepare as follows:

[0052] The first step: mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 4 times that of the mixture and be 95% ethanol, heat to boiling and reflux for 3 hours, filter, and slow down the mixture at a rate of 2ml per minute by percolation method. Slow percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.05Mpa to a paste with a relative density of 1.00 at 70°C, and spray dry. The air inlet temperature of the spray dryer is 180°C, and t...

Embodiment 2

[0054] Embodiment 2 oral liquid

[0055] Take 180g of horizontal sutra mat, 220g of Zoumatai, 70g of chrysanthemum, 80g of black sesame, 240g of lotus, 220g of mussel, 420g of ginseng, 110g of shayuanzi, 170g of shanxiangguo, 140g of nanzhuzi, 440g of euonymus , 60g of stone brush handle, 120g of Xuemancao, 80g of Luxiancao, 90g of Lao Lai Qing, 160g of Daye Qianjin root, 180g of thorn fruit vine and 110g of Heipi Dieda;

[0056] Prepare as follows:

[0057] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate un...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for curing liver-kidney asthenia femoral head necrosis and a preparation method thereof. The traditional Chinese medicine comprises the following crude drugs: membranaceous beautyleaf roots, giantleaf ardisia rhizome, Aristolochia impressinervis C. F. Liang, black sesame seeds, adenia chevali, mussel, roots of wallich swallowwort, flatstem astragalus seeds, Lindera metcalfiana Allen var.dictyophylla (Allen) H. P. Tsui, asiatic bilberry, winter creeper, herb of whixh plant, sambucus adnata, pyrola, the old green, Flemingia macrophylla (Willd.) Prain, byttneria aspera colebr and stems of manyflower fissistigma. The traditional Chinese medicine has an exact curative effect on liver-kidney asthenia femoral head necrosis, and has small toxic and side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating liver and kidney deficiency type necrosis of the femoral head and a preparation method thereof. Background technique [0002] Necrosis of the femoral head is one of the common orthopedic diseases. Common causes are trauma, alcohol consumption, and hormones. The pathogenesis is still unknown. The disease is a progressive and destructive disease. If active and effective treatment is not taken, patients with femoral head necrosis will develop to the collapse of the femoral head and damage the joint function. [0003] At home and abroad, many surgical treatments are used for femoral head necrosis, such as artificial femoral head replacement, drilling decompression, vascular implantation, bone stenting and so on. Due to improper artificial femoral head materials and human body’s own re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P19/08
CPCA61K9/0053A61K9/08A61K9/1652A61K35/618A61K36/11A61K36/185A61K36/264A61K36/27A61K36/35A61K36/37A61K36/45A61K36/48A61K36/481A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 张华李娜郑会梅张建华
Owner 韦标方
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