Hemostatic and anti-adhesion composite material of hydroxyethyl cellulose system and preparation method thereof
A technology of hydroxyethyl cellulose and composite materials, applied in medical science, bandages, absorbent pads, etc., can solve problems such as blurred vision of wounds, difficulty in wound cleaning, and difficult control of spraying range, and achieve the effect of reducing postoperative adhesion and hemostasis Excellent, fast hemostasis effect
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Embodiment 1
[0028] Dissolve the polymer in an organic solvent consisting of DMF, acetone, THF and hexafluoroisopropanol, prepare a polymer mixed solution with a mass volume concentration of 20%, and stir at room temperature for 5 hours to obtain a polymer mixed solution
[0029] 5g of hydroxyethyl cellulose is added with ethanol and water with a volume ratio of 1:1 to form a solution or suspension with a concentration of 0.5%.
[0030] The above-mentioned organic polymer mixed solution was injected into 5 to 8 10ml syringes respectively, and a No. 5 stainless steel pillow (diameter 1 to 5mm) was added. The voltage was 10KV, the solution flow rate was 1ml / h, and the receiving distance was 5cm. Multi-nozzle electrospinning was performed to obtain anti-blocking filaments.
[0031] The above-mentioned hydroxyethyl cellulose solution was injected into 3 to 4 10ml syringes, respectively, and a No. 5 stainless steel pillow (diameter 1 to 5mm) was added. The voltage was 10KV, the solution flow ra...
Embodiment 2
[0034] Dissolve the polymer in an organic solvent consisting of DMF, acetone, THF and hexafluoroisopropanol, prepare a polymer mixed solution with a mass volume concentration of 50%, and stir at room temperature for 24 hours to obtain a polymer mixed solution
[0035] 5g of hydroxyethyl cellulose is added with ethanol and water with a volume ratio of 10:1 to form a solution or suspension with a concentration of 10%.
[0036] The above-mentioned organic polymer mixed solution was injected into 5 to 8 10ml syringes respectively, and a No. 5 stainless steel pillow (diameter 1 to 5mm) was added. The voltage was 30KV, the solution flow rate was 5ml / h, and the receiving distance was 25cm. Multi-nozzle electrospinning was performed to obtain anti-blocking filaments.
[0037] The above-mentioned hydroxyethyl cellulose suspension was injected into 3 to 4 10ml syringes respectively, and a No. 5 stainless steel pillow (diameter 1 to 5mm) was added. The voltage was 30KV, the solution flow...
Embodiment 3
[0040] Dissolve the polymer in an organic solvent consisting of DMF, acetone, THF and hexafluoroisopropanol, prepare a polymer mixed solution with a mass volume concentration of 35%, and stir at room temperature for 12 hours to obtain a polymer mixed solution
[0041] 5g of hydroxyethyl cellulose is added with ethanol and water with a volume ratio of 5:1 to form a solution or suspension with a concentration of 5%.
[0042] The above-mentioned organic polymer mixed solution was injected into 5 to 8 10ml syringes, respectively, and a No. 5 stainless steel pillow (diameter 1 to 5mm) was added. The voltage was 20KV, the solution flow rate was 3ml / h, and the receiving distance was 15cm. Multi-nozzle electrospinning was performed to obtain anti-blocking filaments.
[0043] The above-mentioned hydroxyethyl cellulose suspension was injected into 3 to 4 10ml syringes, respectively, and a No. 5 stainless steel pillow (diameter 1 to 5mm) was added. The voltage was 20KV, the solution flow...
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Abstract
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Application Information
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