Traditional Chinese medicine for treating poultry cold in four seasons and preparation method thereof

A production method and technology of traditional Chinese medicine, applied in the direction of medical formula, non-active ingredient medical preparations, medical preparations containing active ingredients, etc., can solve the problem of uncontrollable absorption rate and active ingredient release rate Low, easy to relapse and other issues, to achieve the effect of avoiding veterinary drug residues and social pollution, high bioavailability, and no toxic side effects

Inactive Publication Date: 2015-03-11
青岛阿普曼生物科技有限公司
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The treatment of poultry flu is mainly based on prevention, and the immunization effect is relatively good. However, due to the influence of factors such as incorrect immunization procedures and poor vaccine quality, it often leads to immunization failure and disease. In some areas, low immunization density causes epidemics.
After the onset of avian influenza, antibiotics and sulfonamides have no therapeutic effect. Although the traditional Chinese medicine powders and oral liquids sold on the market for the treatment of avian influenza have certain curative effects, they are prone to recurrence and cannot be cured.
In addition, in the prior art, compared with tablets and capsules, dosage form pills have the characteristics of slower onset of action and lower bioavailability. Patients usually consider tablets, capsules, and granules with quick onset of action when selecting dosage forms. Dosage and other dosage forms
The traditional extraction method of poultry cold traditional Chinese medicine is the decoction method: add 6-8 times the amount of water of the original medicinal material and directly decoct twice for 1 hour each time, combine the filtrate, and wet granulate with dextrin as the binder. The obtained product has no slow-release and controlled-release function. When the granules pass through the stomach, the active ingredient directly contacts with the gastric juice and is destroyed in a strong acid environment. Moreover, the absorption rate and the release rate of the active ingredient are not controllable, and the blood drug concentration lasts longer. short

Method used

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Embodiment Construction

[0024] A method for preparing a traditional Chinese medicine for treating poultry seasonal cold, characterized in that it specifically comprises the following steps:

[0025] (1) Low-temperature microwave reflux extraction: Mix the above raw materials according to the weight ratio, place them in the extraction tank, add water 4 times the volume of the original medicinal materials, control the temperature between 45-50°C, and extract 2-3 times with microwave ultrasonic, Each 1h, combined filtrate;

[0026] (2) Vacuum and low pressure concentration: raise the temperature of the above filtrate to 65-70°C, and control the vacuum pressure to 25-35KPa

[0027] Concentrate to 30% of the stock solution, add 5-8% polyethylene glycol (PEG), and stir evenly;

[0028] (3) Coating: Put the above concentrated solution into the wet granulator, turn it on and stir, spray into the enteric coating agent, and then put it in the dryer to control the drying temperature at 85-90°C, and dry for 10-...

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Abstract

The invention discloses a traditional Chinese medicine for treating poultry cold in four seasons and a preparation method thereof. The traditional Chinese medicine comprises the following raw materials in percentage by weight: 25 to 35 percent of isatis root, 40 to 45 percent of folium isatidis, 8 to 13 percent of scutellaria baicalensis and 15 to 20 percent of poria cocos in a summer formula; 25 to 35 percent of isatis root,40 to 45 percent of folium isatidis, 8 to 13 percent of schizonepeta and 15 to 20 percent of the root of fangfeng in an autumn formula; 25 to 35 percent of isatis root, 40 to 45 percent of folium isatidis, 4 to 8 percent of cassia twig, 8 to 13 percent of rhizoma zingiberis and 8 to 13 percent of ligusticum wallichii in a winter formula; 25 to 35 percent of isatis root, 40 to 45 percent of folium isatidis, 6 to 8 percent of astragalus mongholicus, 4 to 7 percent of poria cocos, 8 to 12 percent of liquorice and 4 to 7 percent of the rhizome of oriental water plantain in a spring formula. The effect of preventing and treating cold of the traditional Chinese medicine is improved; the dissolution rate of active ingredients can be improved; damage of the high temperature to the active ingredients is reduced; volatilization and sublimation of the active ingredients, which are caused by the high temperature, are reduced; PEG (polyethylene glycol) and enteric coating preparations enable the release rate of the product to be controllable; effective blood concentration is prolonged; the traditional Chinese medicine has no toxic or side effects and is safe to use; the recovery rate of the traditional Chinese medicine for the poultry cold diseases reaches about 95 percent.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine formulas for treating colds, and in particular relates to a traditional Chinese medicine for treating poultry seasonal colds and a preparation method thereof. Background technique [0002] A cold is a conditional disease caused by poor hardware or careless feeding in the process of raising poultry. Simply put, it is an allergic reaction of the animal body. It is mainly caused by the six evils, exogenous evils, and a series of physiological and pathological reactions in the body, referred to as allergic reactions. The seasons are different, the etiology is different, the appearance is different, and the difficulty of secondary treatment is different. According to the changes of the four seasons, colds can be roughly divided into: summer: typhoid fever, which belongs to wind-heat type cold; autumn: cold, which belongs to cold and heat alternating cold; winter: typhoid fever, wh...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K36/704A61K36/855A61K36/538A61K36/9068A61K36/884A61K47/32A61P11/00
CPCA61K36/195A61K9/1635A61K36/076A61K36/236A61K36/238A61K36/315A61K36/481A61K36/484A61K36/538A61K36/539A61K36/54A61K36/704A61K36/855A61K36/884A61K36/9068A61K47/32A61K2236/331A61K2236/39
Inventor 张建青员荣耀田廷超
Owner 青岛阿普曼生物科技有限公司
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