A kind of fosaprepitant dimeglumine composition for injection and preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- CHENGDU EASTON BIOPHARMACEUTICALS CO LTD
- Publication Date
- 2017-03-29
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Abstract
Description
technical field
[0001] The invention relates to a pharmaceutical composition for injection and a preparation process thereof, in particular to a fosaprepitant dimeglumine composition for injection and a preparation method thereof, belonging to the technical field of medicine. Background technique
[0002] Chemotherapy drugs such as platinum, doxorubicin and other antineoplastic drugs can cause severe nausea and vomiting (CIVN) during use. Acute and severe nausea and vomiting may lead to dehydration, electrolyte imbalance, and malnutrition in patients. Severe cases may Bleeding, infection and even death due to damage to the gastrointestinal mucosa make patients fearful of chemotherapy and significantly reduce their compliance, affecting the efficacy of treatment. Therefore, antiemetic drugs are important adjuvant drugs for antitumor therapy. At present, the main chemotherapy antiemetic drugs used clinically are 5-HT antagonists, and the representative drugs are ondansetron an...