Multi-part device for extracting plasma from blood

A multi-part, plasma-based technology used in measuring devices, laboratory containers, sample preparation for testing, etc.

Inactive Publication Date: 2015-04-15
F HOFFMANN LA ROCHE & CO AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, particulate matter that may be in the large storage syrin

Method used

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  • Multi-part device for extracting plasma from blood
  • Multi-part device for extracting plasma from blood
  • Multi-part device for extracting plasma from blood

Examples

Experimental program
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Embodiment Construction

[0022] All variants have filter cartridge 13 as a common element, or sample collection unit (see figure 1 or image 3 Integral assembly of the syringe 11) or a separate part, which is inserted into the sample collection unit by the user (see Figure 4 to Figure 7 The lancing device 12). The filter cartridge 13 comprises a filter unit 10 with a multi-layer filter and a plasma collection container 17 with a conical tip extending towards the filter unit 10 (plasma tip). After plasma extraction, the filter cartridge 13 may be split or separated along the plane ε, resulting in the plasma applicator 14 containing the plasma collection container 17 and the filter housing 8 containing the filter unit 10 .

[0023] exist Figure 1 to Figure 3 The first variant shown in has a filter cartridge 13 integrated in a syringe 11 with a Luer cone 22 formed on the filter housing 8 into which a needle can be inserted. used to collect whole blood samples. In the housing of the syringe 11, a ...

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Abstract

The device has a piston syringe (11) for receiving the blood. A filter unit (10) is provided with a multi-layer film filter for separating the plasma. A piston pump (20) is set for generating low pressure in the filter unit. A plasma collection container (17) is arranged in a filter cartridge (13) and is tapered towards the filter unit. The filter cartridge is isolated after the plasma generation such that a tip (9) of the plasma collection container is set free for sample introduction into an analyzer.

Description

technical field [0001] The invention relates to a multi-component device for separating plasma from whole blood, with a sample collection unit for receiving whole blood; a filter unit with a layered filter of multiple layers for extracting plasma; and a pumping unit, A plunger pump is preferred for creating a partial vacuum in the filter unit. The invention further relates to a filter cartridge with a multilayer filter unit for separating plasma from whole blood. Background technique [0002] For the separation of plasma from whole blood, in addition to the centrifuges mainly used in laboratories, a large number of devices are known for obtaining very small amounts of plasma by separating plasma from whole blood by means of filtration at point-of-care (PoC). [0003] In the simplest case, plasma separation can be achieved by means of a multilayer test strip as described in DE 40 15 589 A1 (BOEHRINGER MANNHEIM), where a transmission layer on an inert carrier layer is provide...

Claims

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Application Information

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IPC IPC(8): B01D33/01G01N33/49G01N1/40A61B10/00B01L3/00
CPCB01L3/502B01L3/5635B01L2400/0478B01L3/5021G01N33/491B01L2300/0681B01L2200/0621A61M1/3616
Inventor H. 许默
Owner F HOFFMANN LA ROCHE & CO AG
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