A microfluidic liquid wave conduction chemiluminescence detection device

Abstract

The invention discloses a micro-fluidic liquid waveguide electrochemical luminescence detection device comprising a chip, an optical waveguide and a signal detector, wherein the chip is provided with a sample flow passage and a waveguide flow passage; the sample flow passage is used for injecting sample liquid; the waveguide flow passage is used for injecting waveguide fluid to form liquid waveguide; one end of the waveguide flow passage is close to the sample flow passage, and the waveguide flow passage is not communicated with the sample flow passage; the two ends of the optical waveguide are connected with the waveguide flow passage and the signal detector respectively; voltage is applied to the sample liquid in the sample flow passage, and the sample liquid in the sample flow passage generates electrochemical reaction under the action of electricity to radiate signal light; and the signal light sequentially penetrates through the liquid waveguide formed by the waveguide flow passage and the optical waveguide and then is collected by the signal detector. The micro-fluidic liquid waveguide electrochemical luminescence detection device provided by the invention is compact in design and simple in structure, has the effects of reducing the usage amount of the sample liquid and performing fixed point detection, and meets use requirements.

Description

technical field [0001] The invention relates to the field of electrochemistry, in particular to a microfluidic liquid wave electrochemistry luminescence detection device. Background technique [0002] Electrochemiluminescence occurs by applying a certain voltage on the electrode to cause the solution components to undergo an electrochemical reaction at the electrode to produce chemiluminescence. The reactant itself or the reaction product in the solution component will undergo a chemical reaction with other components in the solution component, and the energy released in the chemical reaction will cause a certain substance in the solution to be excited and release the energy in the form of light radiation. By detecting the radiated light signal, the purpose of analyzing the reactant can be realized. The electrochemiluminescence analysis method has the advantages of simple equipment, good reproducibility, no background light interference, and high sensitivity. However, the ...

AI Technical Summary

Problems solved by technology

However, the current conventional electrochemiluminescence devices usually place the solution components in a sample cell of the order of milliliters and use a photomultiplier tube directly placed on the sample cell to collect and count the radiated light for detection. On the one hand, this device The consumption of solution components is large. On the other hand, due to the wide collection of light areas, fixed-point analysis cannot be performed, which cannot meet the requirements of use.

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