Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition for improving sleep and preparation method thereof

A technology for improving sleep and composition, which is applied in the field of composition for improving sleep and its preparation, and can solve problems such as unrecognized effects, lack of energy, and increased burden on the liver and kidneys, achieving non-toxic side effects, improving sleep, and improving falling asleep The effect of incidence

Active Publication Date: 2015-07-08
GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
View PDF2 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, not only the effects of these drugs are mostly unaffirmed, but most sleeping pills are metabolized by the liver and kidneys in the body. Long-term use will increase the burden on the liver and kidneys, and some will cause liver enlargement, pain in the liver area, jaundice, and edema , proteinuria, hematuria and nausea, abdominal distension, loss of appetite, constipation and other liver and kidney damage and gastrointestinal reactions
Some sleeping pills can also cause accumulated poisoning symptoms such as lack of energy, mental decline, and blood pressure drop, and even cause respiratory and circulatory dysfunction.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition for improving sleep and preparation method thereof
  • Composition for improving sleep and preparation method thereof
  • Composition for improving sleep and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] The preparation of embodiment 1 apple stem cell freeze-dried powder

[0093] 1. The formula of the culture medium:

[0094] 1.1 Induction medium: MS solid medium + NAA0.5mg / L + BA 2mg / L + CH 1mg / L, pH value is 6.0;

[0095] 1.2 Proliferation medium: MS liquid medium+2,4-D 2.0mg / L+BA 1.0mg / L+CH1.0mg / L+AC 1.0mg / L, pH value is 6.0;

[0096] 2. Sterilization of apple branches

[0097] Choose green-planted apple trees free of chemical fertilizer and pesticide pollution, and select 10 10cm-long new shoots according to certain criteria; wash the surface attachments on the new shoots with 2L of sterile water; soak the new shoots in 120mg / L L-ascorbic acid 1 minute; sterilize new shoots in 75% ethanol solution for 1 minute, rinse with 2L sterile water; put them in 30% hydrogen peroxide solution for sterilization for 20 minutes, and rinse with sterile water for 10 minutes.

[0098] 3. Induction of cambium tissue

[0099] Use an inoculation knife to peel off the cambium, phloe...

Embodiment 2

[0108] Embodiment 2 improves the preparation of sleep composition

[0109]First, 100 g of apple stem cell freeze-dried powder, 100 g of spinous date seed extract, and 40 g of γ-aminobutyric acid were pulverized respectively (wherein, the apple stem cell freeze-dried powder was ground with liquid nitrogen, and the spinous date seed extract and γ-aminobutyric acid were generally Grinding), passing through a 100-mesh sieve, and then mixing the pulverized and sieved materials evenly in a mixer.

Embodiment 3

[0110] Embodiment 3 improves the preparation of sleep composition

[0111] First, 100 g of apple stem cell freeze-dried powder, 100 g of spinous date seed extract, and 75 g of gamma-aminobutyric acid were pulverized respectively (wherein, the apple stem cell freeze-dried powder was ground with liquid nitrogen, and the spinous date seed extract and gamma-aminobutyric acid were generally Grinding), passing through a 100-mesh sieve, and then mixing the pulverized and sieved materials evenly in a mixer.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of health products and in particular relates to a composition for improving sleep and a preparation method thereof. The composition is characterized in that apple stem cell lyophilized powder, spina date seed extract and gamma-aminobutyric acid are compounded, the effect of obviously improving sleep is realized, and no toxic or side effect is produced. Experiments show that the effect for improving sleep of the provided composition is obviously better than the effects of respective components, and mouse acute toxicity test results show that abnormality is not found on a mouse and no poisoning or death phenomenon is caused; and the provided composition can effectively improve incidence that the mouse at subthreshold dose of pentobarbital sodium falls asleep at a dosage of 0.5g / kg.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a composition for improving sleep and a preparation method thereof. Background technique [0002] The modern fast-paced life and gradually fierce competitions make people more and more mentally stressed. Long-term mental tension and a series of irregular life rhythms cause insomnia that has always troubled most people. According to statistics, my country's insomniacs account for 20% to 30% of the total population, and middle-aged and elderly people account for about 70%. Long-term insomnia can easily cause restlessness, fatigue, and even headache, dreaminess, sweating, and memory loss. It can also cause a series of clinical symptoms and induce some psychosomatic diseases. The reduction of work efficiency due to physical ailments increases the psychological pressure of insomniacs. Such a vicious circle leads to neurasthenia, endocrine disorders, etc., and even develo...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/73A61P25/20A61K31/197
Inventor 陈海佳王一飞葛啸虎黎娟妹戴国胜舒辉萍
Owner GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com