Microfluidic chip with autonomous microfluidic movement, manufacturing method, and liquid injection device
A technology of microfluidic chip and liquid injection device, which is applied in the direction of chemical instruments and methods, laboratory containers, laboratory utensils, etc., which can solve the problem of insufficient quality of flow channel surface, insufficient flexibility of fluid drive, and easy leakage of packaging. Liquid and other problems, to achieve the effect of easy fluid flow, light weight, high efficiency, and high production efficiency
Active Publication Date: 2017-01-04
SOUTH CHINA UNIV OF TECH
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Problems solved by technology
The fabrication, packaging and driving method of the microfluidic chip described in the present invention can effectively solve the problem that the surface quality of the flow channel in the current microfluidic chip is not high enough, the packaging is prone to liquid leakage, the equipment is expensive and costly, the fluid drive is not flexible enough, and the equipment is complicated, etc. question
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[0040] In order to better understand the present invention, the present invention will be further described below in conjunction with the accompanying drawings and examples, but the protection scope of the present invention is not limited to the range indicated by the examples.
[0041] Such as figure 1 As shown, a microfluidic chip with microfluidic autonomous movement includes a chip substrate 1 and a cover plate 17. The chip substrate 1 is provided with a microfluidic channel 2 with a V-shaped groove in cross section. The microfluidic channel 2 The depth of the inlet is 10-800 microns, and the depth of the outlet of the flow channel is 20-800 microns. At the same time, the depth of the micro-channel 2 gradually becomes deeper from the entrance to the outlet, and the change law is ΔH=ΔLtanβ, ΔH is the increment of the depth of the flow channel, ΔΔ is the increment of flow channel length, 0<β<10 degrees.
[0042] Further, the micro-channels 2 are radially distributed on the ...
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The invention discloses a micro-fluidic chip containing microfluid in self-discipline movement. The micro-fluidic chip comprises a chip substrate and a cover plate; a micro channel with a V-shaped cross section is arranged in the chip substrate, the depth of the inlet of the micro channel is 10 to 800 micrometers, the depth of the outlet of the micro channel is 20 to 800 micrometers, at the same time, the depth of the micro channel increases from the inlet to the outlet, the changing rule of the depth is accord with a formula: [delta]H=[delta]Ltan[beta], wherein in the formula, [delta]H represents the increased amount of depth of the micro channel, [delta]L represents the increased amount of the length of the micro channel, and 0 degree<beta<10 degrees. The provided micro-fluidic chip has the advantages of high precision in moulding, higher quality of internal wall surface of the micro channel, more easiness for fluid flowing, simpler technology, higher production efficiency, and lower cost. The invention further provides a manufacturing method of the micro-fluidic chip and a liquid injecting device for the micro-fluidic chip. The injecting device has the following advantages: the encapsulation is tight, the technology is simple, and the encapsulation efficiency is high.
Description
technical field [0001] The invention relates to a microfluidic chip, in particular to a microfluidic chip with autonomous microfluidic movement, a manufacturing method, and a liquid injection device. Background technique [0002] Microfluidic chip is a highly integrated product of micro-electromechanical processing technology, test analysis technology, digital information technology, etc. It integrates biochemical analysis, separation, medical virus, gene detection and other functions into one chip. With the development of information technology, using microfluidic chip detection technology, remote diagnosis and telemedicine can be realized. The microfluidic chip uses its internal microchannels to separate, mix, and react test fluids and sample fluids according to different requirements to achieve its functions. Generally, the width of microchannels is as small as 50 microns, and the depth 10 microns. At present, microfluidic channels on the surface of microfluidic chip su...
Claims
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IPC IPC(8): B01L3/00
Inventor 谢晋司贤海冯彦科江宇宁
Owner SOUTH CHINA UNIV OF TECH