Application of traditional Chinese medicine composition in preparation of drug used for resisting influenza A (H3N2) virus

A technology of H3N2 and composition, applied in the application field of traditional Chinese medicine

Inactive Publication Date: 2015-08-12
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Neuraminidase exists on both type A and type B influenza viruses, so oseltamivir is effective for both type A and type B influenza virus infections. The drug greatly reduces the virus that is spread through sneezing, but it cannot completely to stop

Method used

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  • Application of traditional Chinese medicine composition in preparation of drug used for resisting influenza A (H3N2) virus
  • Application of traditional Chinese medicine composition in preparation of drug used for resisting influenza A (H3N2) virus
  • Application of traditional Chinese medicine composition in preparation of drug used for resisting influenza A (H3N2) virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0114] The raw material drug formula is:

[0115] Forsythia 255 g Honeysuckle 255 g Radix Isatidis 255 g Rhubarb 51 g Patchouli 85 g

[0116] Mianma Guanzhong 255g Rhodiola 85g Menthol 7.5g Honey Ephedra 85g

[0117] Fried bitter almonds 85 g Houttuynia cordata 255 g Licorice 85 g Gypsum 255 g

[0118] The preparation method is:

[0119] (1) Weigh Chinese herbal medicines according to the above prescription, select them cleanly, and break them into pieces as appropriate;

[0120] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0121] (3) Forsythia, Ephedra, Houttuynia cordata, and rhubarb, extract twice with 8 times the amount of 70% ethanol, the first time for 2 hours, and the second time for 1.5 hours, the extracts are combined and filtered, the ethanol is recovered, and...

Embodiment 2

[0126] The raw material drug formula is:

[0127] Forsythia 280g Honeysuckle 240g Isatidis 280g Rhubarb 45g Patchouli 90g Mianma Guanzhong 240g Rhodiola 70g Menthol 6g Ephedra 90g Bitter almond 70g Houttuynia cordata 280g Licorice 70g Gypsum 280g

[0128] The preparation method is:

[0129] (1) Weigh Chinese herbal medicines according to the above prescription, select them cleanly, and break them into pieces as appropriate;

[0130] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0131] (3) Forsythia, Ephedra, Houttuynia cordata, and rhubarb, extract twice with 6 times the amount of 50% ethanol, the first time for 3 hours, and the second time for 1 hour, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for later use;

[0132] (4) Ho...

Embodiment 3

[0136] The raw material drug formula is:

[0137] Forsythia 240 g Honeysuckle 280 g Isatidis 240 g Rhubarb 55 g Patchouli 70 g Mianma Guanzhong 280 g Rhodiola 90 g Menthol 8 g Ephedra 70 g Bitter almond 90 g Houttuynia cordata 240 g Licorice 90 g Gypsum 240 g g.

[0138] The preparation method is:

[0139] (1) Weigh Chinese herbal medicines according to the above prescription, select them cleanly, and break them into pieces as appropriate;

[0140] (2) Patchouli is broken, add 10 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0141] (3) Forsythia, Ephedra, Houttuynia cordata, and rhubarb, extract twice with 10 times the amount of 90% ethanol, the first time for 1 hour, and the second time for 3 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for later us...

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PUM

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Abstract

The invention discloses application of a traditional Chinese medicine composition in preparation of a drug used for resisting the influenza A (H3N2) virus. The traditional Chinese medicine composition is composed of fructus forsythia, honeysuckle flower, ephedra stem, bitter apricot kernel and the like, has wide-spectrum antiviral effect and can effectively kill viruses, bring down a fever and diminish inflammation; and experiments prove that the traditional Chinese medicine composition is definitely capable of resisting the influenza A (H3N2) virus.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of anti-influenza A (H3N2) virus medicine, which belongs to the field of traditional Chinese medicine application. Background technique [0002] Influenza A virus H3N2 subtype is a kind of influenza A virus, which is a respiratory disease caused by myxovirus, which can be transmitted through the respiratory tract of various animals. Patients often show symptoms of common influenza, and sometimes Diarrhea and vomiting, severe cases may develop secondary pneumonia, respiratory failure, and even death. [0003] At present, vaccination is the main way to prevent influenza A H3N2 virus; there is no particularly effective drug for the treatment of influenza virus, and oseltamivir phosphate is mainly recommended. 98.5 mg of oseltamivir phosphate (equivalent to 75 mg of osel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/78A61K9/48A61K9/20A61K9/14A61K9/16A61K9/08A61K9/02A61K9/06A61K9/12A61P31/16A61P11/00A61K31/045A61K33/06
Inventor 张彦芬刘丽杰唐思文王海荣
Owner HEBEI YILING MEDICINE INST
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