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Application of Yixuanning Granules in the preparation of medicaments for the treatment of acute heat convulsion and limb convulsions in children

A technology for twitching limbs and suppressing dizziness, which is applied in the directions of drug combinations, pharmaceutical formulas, plant raw materials, etc., to achieve the effects of easy portability, good taste, and easy storage.

Active Publication Date: 2018-07-03
TONGHUA MAOXIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Indications for the treatment of hyperactivity of liver yang and vertigo of both qi and blood deficiency, and its application in the preparation of medicines for the treatment of acute heat convulsions and convulsions of limbs in children has not been reported

Method used

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  • Application of Yixuanning Granules in the preparation of medicaments for the treatment of acute heat convulsion and limb convulsions in children

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0016] Application of Yixuanning Granules in the preparation of medicines for treating children with acute heat and convulsions and convulsions of limbs; said Yixuanning Granules are made of the following medicines: Dannanxing 75g, Lycium barbarum 100g, Pig Tieluo 75g, Oyster (calcined) 100g , Poria cocos 100g, chrysanthemum 75g, cocklebur (fried) 100g, white peony 75g, bamboo 75g, scutellaria baicalensis 75g, hawthorn 50g, tangerine peel 75g. For the above twelve flavors, take pig iron powder, oysters, add appropriate amount of water, and cook for 2 hours, then add cocklebur, chrysanthemum, Dannanxing, Zhuru, and tangerine peel and continue to cook for three times, successively for 1, 1, and 0.5 hours, and then filter. After passing, the filtrates were combined, and the filtrate was concentrated to a clear paste with a relative density of 1.0-1.2 (80-90°C). The remaining scutellaria baicalensis, white peony root, poria cocos, hawthorn, medlar, etc. were decocted twice with wa...

experiment example

[0018] Clinical Trials

[0019] Clinical trials were conducted on 39 children with acute fever, convulsions and limb convulsions (as shown in the table below):

[0020] age gender

0-1 years old

1-2 years old

2-3 years old

3-5 years old

total

male

3

5

4

2

14

female

2

9

8

6

25

total

5

14

12

8

39

[0021] The above 39 patients all had acute fever and convulsions and convulsions of limbs as the main symptoms, including 14 males and 25 females; aged 0-5 years, with an average of 2.19 years; the course of disease ranged from 3 months to 5 years, with an average of 2.81 years.

[0022] Dosing method: Take Yixuanning Granules orally, 1 bag at a time, 3 times a day, 28 days as a cycle, 2 cycles in total, those who are effective can continue to take the medicine according to the situation, up to 6 cycles. Follow up for three years.

[0023] Diagnostic criteria: formulated with refer...

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Abstract

The invention relates to a new application of traditional Chinese medicine preparation, namely, an application of suppression dizzy granules in preparation of medicine for curing infantile thermal shock infantile convulsions and convulsions of limbs. The suppression dizzy granules have the functions of calming the liver, decreasing internal heat and removing phlegm, nourishing blood and tonifying the spleen and dispelling of wind and clearing heat, curing hyperactivity of liver-yang and curing qi-blood deficiency type vertigo and curing the infantile thermal shock infantile convulsions and the convulsions of the limbs at the same time. Through clinical observation of 39 patients which have the infantile thermal shock infantile convulsions and the convulsions of the limbs, the curing rate is 92.31%. The suppression dizzy granules have the advantages of being convenient to carry and to take, good in taste, easy to store, stable in effective composition of herbs, small in side effect and free of drug dependence.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine preparation, that is, the application of Yixuanning Granules in the preparation and treatment of acute fever convulsions and convulsions of limbs in children. Background technique [0002] Convulsion is a common acute and severe disease in childhood, which is caused by various reasons and diseases. Clinically, the main symptoms are stiff neck, twitching of limbs, and even opisthotonus, or accompanied by unconsciousness or even coma. Convulsion is a syndrome, which is more common in infants aged 1 to 5, and the younger the age, the highest incidence rate can occur all year round. It can be divided into acute convulsions and slow convulsions, which are called infantile convulsions in Western medicine. [0003] Traditional Chinese medicine believes that the cause of convulsions is mainly caused by exogenous six evils and epidemic poisons, and occasionally caused by violent shock...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P25/08A61P21/00A61K35/618A61K33/26
Inventor 王茂祥贺天鹏蔡福珍胡凤玲王雪
Owner TONGHUA MAOXIANG PHARMA