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Tannic acid pH-stable hemorrhoid gel and preparation method thereof

A stable, tannic acid technology, applied in the field of medicine, can solve problems such as influence, loss of lasting effect, convergence and healing of hemorrhoids, etc., and achieve the effects of short course of treatment, no toxic side effects, and stable pH value.

Inactive Publication Date: 2015-10-14
ZHEJIANG HONGYU MEDICAL COMMODITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The PH value of tannic acid acting on hemorrhoids to exert its maximum astringent and healing effect is PH=4.6. However, after the common tannic acid ointment (or gel) on the market is applied to hemorrhoids, the PH value is quickly affected by the anus and feces and becomes weakly alkaline. As a result, the continuous effect of astringent and healing of hemorrhoids has been lost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Tannic acid pH stable hemorrhoid gel is made from the following raw materials in parts by weight: 10 parts of tannic acid, 3 parts of carbomer, 2 parts of polyhexamethyleneguanidine, 3 parts of lithium magnesium silicate, 2 parts of dry alum, 4 parts of red stone fat, 1 part of stove heart soil, 3 parts of glycerin, 0.5 parts of potassium hydrogen phthalate, 2 parts of aloe vera flower, 3 parts of poplar leaf, 1 part of acacia bark, 3 parts of milkwort grass, 2 parts of sweet potato vine, Deionized water in moderation.

[0030] The preparation method of tannic acid pH stable hemorrhoid gel comprises the following steps:

[0031] (1) Mix aloe vera flowers, poplar leaves, Albizia Julibrissin, milkwort grass, and sweet potato vines evenly, add water to boil twice, add 8-10 times the water for the first time, boil for 1-2 hours, and add water for 6-8 times for the second time times, decocted for 1-2h, combined decoction, filtered, the filtrate was concentrated to a thick p...

Embodiment 2

[0037] Tannic acid pH stable hemorrhoid gel is made from the following raw materials in parts by weight: 12 parts of tannic acid, 5 parts of carbomer, 3 parts of polyhexamethyleneguanidine, 4 parts of lithium magnesium silicate, 2.5 parts of dry alum, 5 parts of red stone fat, 1.5 parts of stove heart soil, 4 parts of glycerin, 0.6 parts of potassium hydrogen phthalate, 2.5 parts of aloe flower, 3.5 parts of boxwood leaf, 1.5 parts of Albizia juniper, 3.5 parts of milkwort grass, 2.5 parts of sweet potato vine, Deionized water in moderation.

[0038] The preparation method is the same as in Example 1.

Embodiment 3

[0040] Tannic acid pH stable hemorrhoid gel is made from the following raw materials in parts by weight: 15 parts of tannic acid, 6 parts of carbomer, 4 parts of polyhexamethyleneguanidine, 5 parts of lithium magnesium silicate, 3 parts of dry alum, 6 parts of red stone fat, 2 parts of stove heart soil, 5 parts of glycerin, 0.8 parts of potassium hydrogen phthalate, 3 parts of aloe flower, 4 parts of poplar leaf, 2 parts of Albizia juniper, 4 parts of milkwort, 3 parts of sweet potato vine, Deionized water in moderation.

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PUM

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Abstract

The invention discloses a tannic acid pH-stable hemorrhoid gel and a preparation method thereof. The gel is prepared from the following raw materials, by weight: 10-15 parts of tannic acid, 3-6 parts of carbomer, 2-4 parts of polyhexamethylene guanidine, 3-5 parts of lithium magnesium silicate, 2-3 parts of dried alum, 4-6 parts of red halloysite, 1-2 parts of oven subsoil, 3-5 parts of glycerin, 0.5-0.8 part of potassium acid phthalate, 2-3 parts of aloe flower, 3-4 parts of Chinese littleleaf box leaf, 1-2 parts of albizia bark, 3-4 parts of euphorbia hirta, 2-3 parts of sweet potato vine, and a proper amount of deionized water. The tannic acid gel is stable in pH value, wherein the pH value can be kept at 4.5-4.8, and the efficacy of treating and curing hemorrhoid can be greatly developed. In the tannic acid gel, traditional Chinese medicine raw materials of aloe flower, Chinese littleleaf box leaf, and the like are added, match one another, and have the efficacy of dissipating stasis to relieve pain, stopping blood and dispersing swelling, dispelling slough and promoting tissue regeneration, sterilizing and detoxifying the body, killing worm and relieving itching, and the like. According to a synergistic effect of tannic acid and polyhexamethylene guanidine, lithium magnesium silicate, and other traditional Chinese medicine raw materials, the tannic acid gel has an obvious effect on curing hemorrhoid, is short in treatment course and reliable in effect, and has no toxic or side effect.

Description

technical field [0001] The invention relates to a tannic acid pH-stable hemorrhoid gel and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Hemorrhoids are one or more soft vein groups formed by varicose veins at the bottom of the anorectum and the anal mucosa, which are directly affected by the anal environment. In the anus, the ammonia gas in the feces is easily soluble in water to form ammonia water. The ammonia water is alkaline, which also makes the pH value of the anus environment alkaline, about PH=8.5. The PH value of tannic acid acting on hemorrhoids to exert its maximum astringent and healing effect is PH=4.6. However, after the common tannic acid ointment (or gel) on the market is applied to hemorrhoids, the PH value is quickly affected by the anus and feces and becomes weakly alkaline. Thereby lost the effect of sustained effect astringent to heal hemorrhoids. Contents of the invention [0003] The obje...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/886A61K47/12A61K9/06A61P9/14A61K33/06A61K33/26A61K33/12A61K31/785A61K31/7024
Inventor 曾菊红
Owner ZHEJIANG HONGYU MEDICAL COMMODITY
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