Application of lipopolysaccharide-binding protein in the preparation of rheumatoid arthritis-related drugs
A technology for combining proteins and lipopolysaccharides, which can be used in drug combinations, peptide/protein components, antipyretics, etc., to solve problems such as no correlation and no research on mutual relationships
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[0029] Example: Research on the role of lipopolysaccharide-binding protein in the diagnosis and disease activity of rheumatoid arthritis
[0030] 1. Case and control sample selection criteria
[0031] The 120 RA patients were all inpatients in the Department of Rheumatology and Immunology, Peking University People's Hospital from 2013 to 2014. They met the RA classification criteria established by the American College of Rheumatology (ACR) in 1987. Among them, 92 were female and 28 were male. 29 to 89 years old, with an average age of 60.27±10.59 years, and the course of disease ranged from 1 to 51 years, with an average of 12.16±8.69 years. A total of 32 patients with osteoarthritis (Osteoarthritis, OA), 30 patients with systemic lupus erythematosus (SLE), and 30 patients with primary Sjögren's syndrome were selected. syndrome, pSS) patients as the disease control group, and 51 healthy volunteers as the healthy control group (HC). The sera of each group were derived from t...
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