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Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis

A hemodynamic and coronary technology, applied in calculation, health index calculation, computer-aided medical procedures, etc., can solve problems such as pressure reduction

Active Publication Date: 2015-11-25
SIEMENS HEALTHCARE GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the use of pressure for invasive pressure measurements involves insertion of a pressure wire into the stenosed vessel with the inherent risks associated with the intervention, and for very narrow stenosis, the pressure wire can result in additional pressure reduction

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  • Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis
  • Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis
  • Method and system for non-invasive computation of hemodynamic indices for coronary artery stenosis

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Embodiment Construction

[0022] The invention relates to a method and system for non-invasive calculation of hemodynamic indexes of coronary artery stenosis by using medical image data and blood flow simulation. Embodiments of the invention described herein allow for a method of visually understanding the simulated blood flow and assessing coronary artery stenosis. Digital images typically include digital representations of one or more objects (or shapes). A digital representation of an object is generally described herein in terms of recognizing or manipulating that object. Such operations are virtual operations implemented in memory or other circuitry / hardware of the computer system. Accordingly, it is to be understood that embodiments of the present invention may be performed in a computer system using data stored in the computer system.

[0023] figure 1 A method for non-invasive calculation of hemodynamic indexes of coronary artery stenosis according to an embodiment of the present invention i...

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Abstract

A method and system for non-invasive hemodynamic assessment of coronary artery stenosis based on medical image data is disclosed. Patient-specific anatomical measurements of the coronary arteries are extracted from medical image data of a patient. Patient-specific boundary conditions of a computational model of coronary circulation representing the coronary arteries are calculated based on the patient-specific anatomical measurements of the coronary arteries. Blood flow and pressure in the coronary arteries are simulated using the computational model of coronary circulation and the patient-specific boundary conditions and coronary autoregulation is modeled during the simulation of blood flow and pressure in the coronary arteries. A wave-free period is identified in a simulated cardiac cycle, and an instantaneous wave-Free Ratio (iFR) value is calculated for a stenosis region based on simulated pressure values in the wave-free period.

Description

[0001] Cross References to Related Applications [0002] The present application claims the benefit of priority to US Patent Provisional Application No. 61 / 990,775, filed May 9, 2014, the contents of which are hereby incorporated by reference. technical field [0003] The present invention relates to the non-invasive functional evaluation of coronary artery stenosis, in particular to the non-invasive functional evaluation of coronary artery stenosis based on medical image data and blood flow simulation. Background technique [0004] Cardiovascular disease (CVD) is the leading cause of death worldwide. Among CVDs, coronary artery disease (CAD) accounts for nearly half of these deaths. Despite significant improvements in medical imaging and other diagnostic methods, early morbidity and mortality increases in CAD patients remain high. Current clinical practice for the diagnosis and management of coronary stenosis involves evaluation of diseased vessels either visually or by q...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/026A61B5/021G06F19/12
CPCG06T7/00A61B5/02007A61B5/02028A61B5/7278A61B2576/00A61B2576/023G06F19/3431G06F19/3437G06T2207/10116G06T2207/30048G06T2207/30104G16H50/30G16H50/50G16H30/40
Inventor L·M·伊图P·沙尔玛T·雷德尔B·乔治斯库
Owner SIEMENS HEALTHCARE GMBH
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