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Method and device for correcting optical signals

An optical signal, signal value technology, used in the field of monitoring implants, can solve problems such as difficulty in glucose reading

Active Publication Date: 2015-12-02
PROFUSA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although this method provides some optical signal correction for background luminescence and reflectance, it may still be difficult to obtain accurate and / or consistent glucose readings from glucose-binding molecules in the epidermis

Method used

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  • Method and device for correcting optical signals
  • Method and device for correcting optical signals
  • Method and device for correcting optical signals

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Embodiment Construction

[0027]In the following description, it should be understood that all described connections between structures may be direct operative connections or indirect operative connections through intermediate structures. A set of elements consists of one or more elements. Any description of an element is to be understood as referring to at least one element. A plurality of elements includes at least two elements. The steps of any described method do not have to be performed in the particular order presented, unless otherwise required. A first element (eg, data) derived from a second element includes the first element equal to the second element, and the first element generated by processing the second element and optionally other data. Making a determination or decision based on a parameter includes making a determination or decision based on the parameter and optionally other data. Unless otherwise specified, an indicator for some quantity / data may be the quantity / data itself, or ...

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Abstract

An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background.

Description

[0001] Related Application Cross Reference [0002] This application claims the benefit of US Provisional Patent Application 61 / 785,087, filed March 14, 2013, entitled "Method and Device for Correcting Optical Signals," which is hereby incorporated by reference in its entirety. Background technique [0003] The present invention relates to methods and devices for monitoring implants, and in particular to methods and devices for correcting luminescence signals emitted from implants. [0004] In certain individuals, monitoring of analyte (eg glucose, lactate or oxygen) levels is important to their health. High or low levels of glucose, or other analytes, may adversely affect or indicate a particular health state. Glucose monitoring is particularly important for individuals with diabetes, a subset of whom must determine when insulin is needed to lower their body's glucose levels or when additional glucose is needed to raise their body's glucose levels. [0005] Conventional tec...

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Application Information

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IPC IPC(8): A61B5/1455
CPCA61B5/1459A61B5/14532A61B5/7203
Inventor G·J·肯兹W·麦克米伦N·维希涅夫斯基
Owner PROFUSA
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