Chinese traditional medicine preparation of licorice and sophora alopecuroides spray and preparation method thereof
The technology of a traditional Chinese medicine preparation and spray, which is applied in the field of traditional Chinese medicine, can solve the problems of aggravation of disease, unsuitable long-term use, inducing erythroderma, etc., and achieves the effects of low cost, improvement of skin itching, and significant clinical efficacy.
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Embodiment 1
[0020] (1) Remove impurities from licorice and bitter beans, wash them, and dry them at a low temperature of 50-60°C;
[0021] (2) Glycyrrhizae, crushed, reflux extracted with 10 times the amount of 70% (v / v) ethanol twice, each time for 1.5h, combined the extracts, and filtered;
[0022] (3) Ethanol is recovered from the above solution, and concentrated to a crude drug amount of 0.8g / ml;
[0023] (4) Adsorb on the AB-8 and D101 (1:1) mixed resin column at a rate of 5 times the column volume / hour;
[0024] (5) Wash 1 times the volume of the column with purified water, backwash with 2.5 times the volume of the column with 80% (v / v) ethanol, recover the ethanol solution, and concentrate to a relative density of 1.11g / cm 3 (20°C), licorice extract;
[0025] (6) Broken the bitter beans, soaked in 15 times the amount of 75% (v / v) ethanol for 5 hours, at a temperature of 50-60°C, and filtered;
[0026] (7) Recover ethanol from the above bitter bean solution and concentrate to a r...
Embodiment 2
[0029] (1) Remove impurities from licorice and bitter beans, wash them, and dry them at a low temperature of 50-60°C;
[0030] (2) Glycyrrhizae, crushed, reflux extracted with 6 times the amount of 70% (v / v) ethanol twice, each time for 1.5h, combined extracts, filtered,
[0031] (3) Ethanol is recovered from the above solution, and concentrated to a crude drug amount of 0.8g / ml;
[0032] (4) Adsorb on AB-8 and D101 (1:1) mixed resin column at a rate of 3 times the column volume / hour;
[0033] (5) Wash 1 times the volume of the column with purified water, backwash with 2.5 times the volume of the column with 80% (v / v) ethanol, recover the ethanol solution, and concentrate to a relative density of 1.11g / cm 3 (20°C), licorice extract;
[0034] (6) Broken the bitter beans, soaked in 15 times the amount of 75% (v / v) ethanol for 5 hours, at a temperature of 50-60°C, and filtered;
[0035] (7) Recover ethanol from the above bitter bean solution and concentrate to a relative densi...
Embodiment 3
[0038] (1) Remove impurities from licorice and bitter beans, wash them, and dry them at a low temperature of 50-60°C;
[0039] (2) Glycyrrhizae, crushed, refluxed with 8 times the amount of 70% (v / v) ethanol for 2 times, each time for 1.5h, combined the extracts, filtered,
[0040] (3) Ethanol is recovered from the above solution, and concentrated to a crude drug amount of 0.8g / ml;
[0041] (4) Adsorb on the AB-8 and D101 (1:1) mixed resin column at a rate of 5 times the column volume / hour;
[0042] (5) Wash 1 times the volume of the column with purified water, backwash with 2.5 times the volume of the column with 80% (v / v) ethanol, recover the ethanol solution, and concentrate to a relative density of 1.11g / cm 3 (20°C), licorice extract;
[0043] (6) Broken the bitter beans, soaked in 15 times the amount of 75% (v / v) ethanol for 5 hours, at a temperature of 50-60°C, and filtered;
[0044] (7) Recover ethanol from the above bitter bean solution and concentrate to a relative...
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