A kind of medical biological nasal cavity fast hemostatic powder and preparation method thereof

A technology for hemostatic powder and nasal cavity, applied in the field of medical materials, can solve the problems of high production cost, long production cycle, complicated preparation process, etc., and achieve the effects of promoting wound healing, shortening coagulation time, and repairing wounds

Active Publication Date: 2018-06-01
DONGGUAN DAQING MEDICAL DEVICES CO LTD +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chitosan-based hemostatic materials are already on the market, but it usually takes a few minutes for a single-component chitosan hemostatic product to promote the formation of a blood clot, so the hemostatic effect is not ideal in the case of large bleeding, and it is difficult to meet the strategic needs. Trauma hemostasis and clinical rapid hemostasis requirements, and the preparation process of sponges, membranes, bandages and other product forms is relatively complicated, the production cycle is long, and the production cost is high

Method used

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  • A kind of medical biological nasal cavity fast hemostatic powder and preparation method thereof
  • A kind of medical biological nasal cavity fast hemostatic powder and preparation method thereof
  • A kind of medical biological nasal cavity fast hemostatic powder and preparation method thereof

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Effect test

Embodiment 1

[0082] A kind of quick hemostatic powder of medical biological nasal cavity, described medical biological quick hemostatic powder of nasal cavity comprises the raw material of following weight portion:

[0083] Puffball Extract 65 parts

[0084] Sodium carboxymethyl cellulose 10 parts

[0085] 1 part large thistle extract

[0086] Imperata root extract 1 part

[0087] Sophora japonica extract 1 part

[0088] 1 part snakeberry extract

[0089] Arborvitae leaf extract 0.5 part.

[0090] The sodium carboxymethylcellulose has a melting point of 270°C and a density of 1.5g / cm 3 croscarmellose sodium.

[0091] The medical biological nasal cavity rapid hemostatic powder also includes 1 part of calcium salt, which is a mixture of calcium lactate, calcium malate and calcium citrate in a weight ratio of 0.8:1:1.5.

[0092] A preparation method of medical biological nasal cavity quick hemostatic powder, comprising the steps of:

[0093] Step A, Weighing: Weigh the puffball extrac...

Embodiment 2

[0097] A kind of quick hemostatic powder of medical biological nasal cavity, described medical biological quick hemostatic powder of nasal cavity comprises the raw material of following weight portion:

[0098] Puffball Extract 70 parts

[0099] Sodium carboxymethyl cellulose 11 parts

[0100] Large thistle extract 2 parts

[0101] 2 parts coriander root extract

[0102] Sophora japonica extract 2 parts

[0103] Snakeberry Extract 2 parts

[0104] 0.8 parts of Arborvitae leaf extract.

[0105] The sodium carboxymethylcellulose has a melting point of 272°C and a density of 1.55g / cm 3 croscarmellose sodium.

[0106] The medical biological nasal cavity rapid hemostatic powder also includes 2 points of sodium alginate, which is a nano-scale ultrafine sodium alginate powder with a particle size of 30nm produced by aerosolized powder making technology.

[0107] A preparation method of medical biological nasal cavity quick hemostatic powder, comprising the steps of:

[0108] ...

Embodiment 3

[0112] A kind of quick hemostatic powder of medical biological nasal cavity, described medical biological quick hemostatic powder of nasal cavity comprises the raw material of following weight portion:

[0113] Puffball Extract 75 parts

[0114] Sodium carboxymethyl cellulose 12 parts

[0115] Large thistle extract 3 parts

[0116] 3 parts coriander root extract

[0117] Sophora japonica extract 3 parts

[0118] 3 parts snakeberry extract

[0119] Arborvitae leaf extract 1.0 parts.

[0120] The sodium carboxymethyl cellulose is cross-linked sodium carboxymethyl cellulose with a melting point of 274° C. and a density of 1.6 g / cm3.

[0121] The medical biological nasal cavity rapid hemostatic powder also includes 3 parts of calcium salt, which is a mixture of calcium lactate, calcium malate and calcium citrate in a weight ratio of 1:1:2.

[0122] The medical biological nasal cavity rapid hemostatic powder also includes 3 points of sodium alginate, which is a nano-scale ultra...

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Abstract

The present invention relates to the technical field of medical materials, in particular to a medical biological rapid nasal cavity hemostatic powder and a preparation method thereof. The medical biological nasal cavity rapid hemostatic powder comprises the following raw materials in parts by weight: 65-85 parts of puffball extract, 10‑14 parts of cellulose sodium, 1‑5 parts of thistle extract, 1‑5 parts of imperina root extract, 1‑5 parts of Sophora japonica flower extract, 1‑5 parts of snakeberry extract and 0.5 parts of oriental cypress leaf extract ‑1.5 servings. The medical biological nasal cavity rapid hemostatic powder of the present invention can play a hemostatic effect through various ways, can obviously shorten the coagulation time, and also has the functions of antibacterial, antibacterial, analgesic, and promoting wound healing, and can be widely used in nasal cavity, oral cavity, The role of rapid hemostasis, pain relief, and wound repair after throat surgery.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a medical biological nasal cavity rapid hemostatic powder and a preparation method thereof. Background technique [0002] Blood coagulation process is very complicated, and there are about 13 factors participating in the reaction, and calcium is one of them. There is a folk practice of burning eggshells to stop bleeding, the principle is the role of calcium. The hemostatic properties of chitosan have been reported in a large number of literatures. The hemostatic mechanism is that positively charged amino groups combine with negatively charged red blood cells and platelet surfaces to form mucoadhesive clots and activate the traditional coagulation pathway. [0003] Chitosan is an alkaline polysaccharide obtained by deacetylation of chitin. Due to the amino group in chitosan molecule, it has many excellent properties such as biocompatibility, biodegradability, hemostasis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/40A61L15/28A61L15/44A61L15/42
Inventor 梁奕福
Owner DONGGUAN DAQING MEDICAL DEVICES CO LTD
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